Ma antibodieswa Angakhudze, koma Osayikiranso Kutentha kwa Hormone ya Chithokomiro
Matenda a m'magazi ndi mapuloteni opangidwa ndi thupi lanu omwe amayankha kapena amayesa kuwononga antigen, zomwe ndi zinthu monga mavairasi ndi mabakiteriya omwe thupi limadziwika kuti ndi achilendo.
Nthawi zina, thupi lanu limalongosola molakwika kuti matenda, ziphuphu, ndi ziwalo zanu sizilendo. Mtundu umenewu umakhala ndi matenda a autoimmune s , ndipo ma antibodies amenewa, omwe amachititsa kuti thupi la munthu liukire molakwika, amatchedwa antiimmune antibodies.
Gulu limodzi la ma antibodies amadzimadzimadzi ndi a khanda la peroxidase (TPO) , ndipo kukhalapo kwawo ("positivity") kumasonyeza kukhalapo kwa matenda a chithokomiro, omwe ambiri amachititsa Hashimoto's thyroiditis.
Kumvetsa Hashimoto's Thyroiditis
Mu chithokomiro cha Hashimoto, ma antibodies a TPO amachititsa kutentha kwa chithokomiro.
Patapita nthaŵi, ma antibodies a TPO amachititsa kutupa ndipo pamapeto pake akhoza kuwononga chiwalo chanu chonse kapena gawo lanu la chithokomiro. Pamene chithokomiro sichitha kuchepetsa kutulutsa timadzi timene timatulutsa timadzi timene timatulutsa timadzi timene timatulutsa timadzi timene timatulutsa timadzi ta tizilombo toyambitsa matenda. Ma antibodies a Hashimoto angapangitsenso chithokomiro chanu kuti chikhale ndi mitsempha, kapena kukulitsa, kudziwika kuti goiter.
Ngakhale zili choncho, zingatenge nthawi kuti chithokomiro chanu chiwonongeke muyeso lanu la testrosi (stimulating hormone) (TSH). Si zachilendo kukhala ndi ma antibodies abwino a TPO kwa miyezi kapena zaka isankhulidwe yanu ya TSH isanakwane mpaka mutapezeka ndi hypothyroidism.
Ndikofunika kunena kuti, kuti anthu ena sapitilira kukhala hypothyroid, ngakhale kuti ali ndi ma antibodies abwino a TPO.
Matenda abwino a TPO, TSH wamba: Kodi chithandizo chili chovomerezeka?
Kawirikawiri, ngati zotsatira zanu zowunikira TSH ndi zachilendo (pakati pa 0,4 ndi 4.5 milliyuni ma unit angapo pa lita imodzi, kapena mU / L), mankhwala (omwe ali ndi kachilombo koyambitsa mankhwala osokoneza bongo) sizitsimikiziridwa, ngakhale ngati TPO zimakhala zabwino.
Komabe, ngati TSH yanu ikukwera mofatsa (tiyeni tizinena mozungulira pafupifupi 6.0mU / L) ndipo hormone yanu ya thyroxine (T4) ndi yachilendo, "mphamvu" ya ma antibodies ya TPO ingayese dokotala wanu kuti ayambe kulandira chithandizo chamatenda a chithokomiro. Izi zili choncho chifukwa chakuti mankhwala oyambirira amalepheretsa kupita patsogolo kwa chonchi chomwe chimatchedwa subclinical hypothyroidism mu overt hypothyroidism.
Dokotala wanu angayesetsedwe kwambiri kuti asamalire matenda a hypothyroidism ngati muli ndi zizindikiro monga kutopa, kudzimbidwa, kapena kupsinjika maganizo, kapena muli ndi matenda ena, mwachitsanzo, matenda a celiac.
Zaka, komanso, zidzathandiza pa chisankho cha dokotala wanu. Kawirikawiri, pamakhala malo apamwamba kwambiri popanga mankhwala a chithokomiro m'malo okalamba, chifukwa mzere wawo woyamba TSH uli pamtunda wapamwamba.
Mawu Ochokera
Mfundo yaikulu apa ndi yakuti ma chitetezo a chithokomiro a peroxidase amasonyeza njira yokhayokha; Komabe, ndi kagawo kakang'ono chabe ka chithokomiro ndipo simukudziwa ngati mukufunikira chithandizo chamatenda a chithokomiro kapena ayi. M'malo mwake, akhoza kukuthandizani ndi chisankho cha dokotala wanu, pakati pa zinthu monga zaka zanu, mbiri ya banja, ndi zizindikiro.
Zonsezi ndi zabwino kuti muyankhule ndi dokotala za zotsatira zanu zapamwamba za labu.
Mwanjira imeneyi mukhoza kutsimikiza kuti mukuyendetsa chithokomiro komanso thanzi lanu lonse.
> Zotsatira:
> Braverman, L, Cooper D. Werner & Ingbar's The Thyroid, 10th Edition. WLL / Wolters Kluwer; 2012.
> Davies TF. Pathogenesis wa Hashimoto's thyroiditis (osachiritsika autoimmune thyroiditis). Ross DS, ed. Zaposachedwa. Waltham, MA: UpToDate Inc.
> Garber, J, Cobin, R, Gharib, H, et. al. Malangizo Okhudza Zipatala za Hypothyroidism M'zochitika Zakale: Ambiri amathandizidwa ndi American Association of Clinical Endocrinologists ndi American Thyroid Association. " Chitetezo cha Endocrine. Mph. 18 No. 6 Novemba / December 2012.
> Jonklaas J et al. Malangizo a Chithandizo cha Hypothyroidism: Wokonzedwa ndi American Thyroid Association Task Force pa Kutentha Hormone m'malo. Chithokomiro . 2014 Dec 1; 24 (12): 1670-1751.
> Kent, Athol. "Matenda a Chithokomiro Okhudzana ndi Kutulutsidwa M'thupi ndi Preterm Birth." Akafukufuku mu Obstetrics ndi Gynecology 4.3-4 (2011): 128-129. 2011.