Zakudya, mankhwala komanso zambiri zimakhudza milandu ya warfarin
Ngati mwachiritsidwa kuti mukhale ndi tizilombo toyambitsa matenda , ndiye kuti mungathe kuyembekezera miyezi itatu ya antiticoagulants kapena mankhwala opopera magazi mutachoka kuchipatala.
Pansi pensa thrombosis ndi chiwopsezo chomwe thupi lanu limapanga chophimba, zomwe zimakhala mwendo, zomwe zingathe kuponyera mbali zina zomwe zingathe kuyendetsa mapapu anu.
Chochitika choopsa ichi chimadziwika kuti embolism yamapangidwe. Mukapitiriza kuchoka kuchipatala mukakhala ndi mankhwala osokoneza bongo , mumachepetsetsa chiopsezo chokonza magazi omwe amafa. Zindikirani, mankhwala a antiticoagulant sikuti amaperekedwa ndi kuya kwambiri thrombosis. Mwachitsanzo, ngati panopa mukuchiritsidwa ndi matendawa kapena matenda enaake, mukhoza kuyembekezera kuti mukhale ndi moyo nthawi zonse.
Anticoagulation ikhoza kusungidwa ndi mankhwala angapo kuphatikizapo otsika-maselo olemera-heparin (jekeseni yapansi), fondaparinux (jekeseni yapansi) kapena pakamwa Xa inhibitors ngati dabigatran. M'nkhani ino, tidzakambirana za warfarin (Coumadin) zomwe zimapezeka ngati mankhwala ovomerezeka. Posankha mankhwala opanga mankhwala, chonde kumbukirani kuti zosankha zilipo, ndipo dokotala wanu angathe kukambirana zomwe mungasankhe.
Momwe Warfarin Amagwirira Ntchito
Warfarin imasokoneza zinthu zowonongeka zomwe zimadalira vitamini K, motero zimayambitsa chisokonezo ndi kuteteza mapangidwe atsopano.
Mpaka mutha kukhazikika, warfarin imayanjanitsidwa ndi marenteral kapena antijectable anticoagulant monga Lovenox (enoxaparin jekeseni).
Warfarin imapezeka m'makonzedwe amodzi ndi amkati-anthu ambiri amatenga warfarin. Anthu ayamba pafupifupi 5 mg wa warfarin tsiku tsiku loyamba. Nthenda ya Warfarin imasinthidwa kuti asunge ma intaneti, miyeso ya chiwonongeko chomwe ine ndikuchikhudza pang'ono, mankhwala.
Ngati mukufuna, webusaitiyi www.warfarindosing.org imapereka chiwerengero cha ufulu wa warfarin-dose calculator.
Ndani Amafunikira Milandu Yapamwamba?
Mankhwala apamwamba a warfarin angafunike kwa odwala otsatirawa:
- African American
- Zosavuta
- Hypothyroid
- Mowa umadalira
Kodi Ndani Akufunika Kuchuluka kwa Mankhwala Ochepa?
Mosiyana ndi zimenezi, anthu odwalawa ayenera kulandira mlingo wochepa wa warfarin:
- Okalamba
- Asia
- Hyperthyroid
- Kulephera kwa mtima
- Matenda a chiwindi
- Mbiri ya opaleshoni yaikulu
- Mapulomphisms mu CYP2C9 kapena majini a VKORC1
Kuwonjezera pa makhalidwe omwe ali pamwambapa odwala, mlingo wa warfarin umasinthidwanso malinga ndi mankhwala omwe mukuwutenga. Mwachitsanzo, phenytoin imachulukitsa chigwirizano cha warfarin ndipo motero amachepetsa ma intaneti.
Ma laboratory muyeso INR (padziko lonse wowerengera chiŵerengero) amagwiritsidwa ntchito kudziwa momwe thupi lanu limakhalira komanso kusintha mlingo wanu wa warfarin. Kwa anthu ambiri, ma intaneti omwe amapezeka mu INR amachokera ku 0.8 mpaka 1.2. Anthu pa warfarin amatha kusunga mlingo wa INR pakati pa 2 ndi 3, kutanthauza kuti odwalawa amadziwika bwino kwambiri (amakhala ndi magazi ochepa kwambiri kuposa anthu ambiri). Pamene mukulandira mankhwala osokoneza bongo, mayendedwe a INR ayenera kuyang'anitsitsa nthawi zonse ndi dokotala wanu.
Mmene Kudya Kumakhudzira Mlingo
Chifukwa warfarin ndi wotsutsana ndi vitamini K, kudya zakudya zambiri mu vitamini K kungachepetse mayendedwe anu a INR.
Makamaka, masamba obiriwira ndi masamba amapezeka kwambiri mu vitamini K. Komatu mbatata, zipatso, ndi tirigu ndizochepa mu vitamini K. Mutha kupitirizabe kudya zakudya zobiriwira ndi masamba obiriwira, komabe yesani kukhala osasinthasintha muzogwiritsidwa ntchito tsiku ndi tsiku kuti ma level anu a INR asasinthe.
Ngozi
Zoipa za mankhwala a warfarin nthawi zambiri zimangokhala ndi nseru, ziphuphu ndi zina zotero. Komabe, warfarin imapangitsa chiopsezo chanu chothetsa magazi kapena kutaya mwazi zomwe zingakhale zovuta kwambiri (ganizirani ubongo wamagazi). Pakadwala kwambiri chifukwa cha mankhwala ndi warfarin, madokotala akhoza kuthandiza vitamini K kuti athandizidwe kapena kutseka magazi.
Anthu omwe ali ndi mbiri ya kuchepa kwa magazi ayenera kusamala mukamenyana ndi warfarin. Komanso, mukamenyera nkhondo, ndi bwino kugwiritsa ntchito lumo lamagetsi ndi magetsi a mano kuti achepetse kutenga magazi. Komanso, onetsetsani kuuza dokotala wanu wa mano kuti muli pa warfarin musanayambe ntchito iliyonse ya mano.
Chifukwa warfarin ikhoza kugwirizanitsa ndi mankhwala osiyanasiyana ndi kuponyera ma intaneti anu mu whack, ndibwino kuti mupewe mankhwala osokoneza bongo kapena mankhwala owonjezera pa mankhwalawa.
Ngati inu kapena wokondedwa wanu mukufuna kutenga warfarin chifukwa cha thrombosis yakuya kwambiri, kupwetekedwa, kapena matenda oopsa, chonde kumbukirani kuti mankhwala a antiticoagulant ndi mankhwalawa amagwira ntchito. Kuti mukhazikitse ndi kusunga malo abwino odziwiratu, muyenera kugwira ntchito limodzi ndi dokotala wanu komanso makamaka odyetserako zakudya. Chonde kumbukirani kuti mukhalebe tcheru, mutengereni ma intaneti anu nthawi zonse, gwiritsani ntchito gulu lanu la thanzi, ndikuyang'anirani zakudya zanu.
> Zotsatira:
> Fogarty PF, Minichiello T. Kusokonezeka kwa Hemostasis, Thrombosis, ndi Antithrombotic Therapy. Mu: Papadakis MA, McPhee SJ, Rabow MW. eds. Kufufuza kwa Zamankhwala Zamakono ndi Chithandizo 2015 . New York, NY: Hill ya McGraw; 2014.
> Mosby's Drug Reference kwa Maphunziro a Zaumoyo, Kachiwiri. Elsevier mu 2010.