Kafukufuku wasonyeza kuti pali kugwirizana pakati pa nikotini ndi matenda opatsirana pogwira (IBD) . Komabe, chododometsa ndi chakuti kusuta kumawoneka kuti kuli ndi zotsatira zosiyana pa mitundu iwiri ya IBD-ulcerative colitis ndi Crohn's disease.
Kulumikizana pakati pa Ulcerative Colitis ndi Kusuta
Ulcerative colitis makamaka amatchedwa matenda a osasuta.
Anthu omwe kale amasuta fodya amakhala pachiopsezo chachikulu chotenga ulcerative colitis, pomwe akusuta tsopano ali ndi chiopsezo chachikulu. Chizoloŵezi chimenechi chimasonyeza kuti kusuta ndudu kungalepheretse kuyamba kwa zilonda za ulcerative.
Ofufuza apeza kuti ndi chikonga cha ndudu za fodya zomwe zimakhudza kwambiri zizindikiro za ulcerative colitis. Nicotine ndizochitika mwachibadwa mu fodya zomwe zimakhudza kwambiri ziwalo zambiri ndi mawonekedwe a thupi. Nthendayi imayambanso kumwa kwambiri, ndipo anthu ambiri amasuta fodya amalephera kusiya ngakhale kuti ndizoopsa kwambiri.
Iwo amavomerezedwa kuti nicotine mu ndudu imakhudza minofu yosalala mkati mwa koloni. Zotsatirazi zingasinthe kutentha kwa moti (chiwerengero chomwe chakudya chikudutsa pamtunda wa GI).
Matenda a Nicotine ndi Crohn
Kusuta fodya kwenikweni kumakhudza matenda a Crohn. Anthu omwe amasuta, kapena omwe amasuta kale, amakhala ndi chiopsezo chachikulu chokhala ndi matenda a Crohn kusiyana ndi osasuta.
Odwala a Crohn omwe amasuta fodya ali ndi kuchuluka kwa kubwereranso ndi kubwereza opaleshoni ndipo zingafunike chithandizo chamagetsi chogonjetsa. Anthu omwe ali ndi matenda a Crohn amalimbikitsidwa kwambiri ndi madokotala awo kuti asiye kusuta kuti athetse vutoli.
Utsi wa Secondhand
Kusuta fodya kwa ana kumakhala ndi zotsatira pa IBD.
Ana omwe amatha kusuta fodya amachepetsa chiopsezo cha ulcerative colitis ndi chiopsezo chowonjezeka cha matenda a Crohn.
Kodi Kale Amene Anasuta Fodya Ali ndi Ulcerative Colitis Kuwala?
Kafukufuku wina wasonyeza kuti kale omwe amasuta fodya omwe amakhala ndi ulcerative colitis ndiyeno amabwerera ku kusuta amakhala ndi zizindikiro zochepa. Komabe, kusuta palokha kumabweretsa mavuto ena aakulu. Madokotala sakanati alangize kuti wodwala ayambe kusuta fodya, chifukwa kuopsa kwa kusuta ndikopambana phindu lililonse .
Nanga Bwanji Zosambira za Nicotine?
Tsopano zizindikiro za chikonga (zomwe zimatchedwanso kuti transdermal chikonga) zilipo chifukwa chosuta fodya, n'zotheka kuphunzira zotsatira za chikonga chokha popanda kuwonetsa thupi ku zoopsa zina za kusuta fodya. Zotsatira za mankhwala nthawi zambiri zimaphunzira ndi kafukufuku omwe amadziwika ngati maphunziro opangidwa ndi awiri omwe amachititsa kuti apeze malo oyenera. Mu phunziro ili, odwala ena amapatsidwa mankhwala atsopano pamene ena amapatsidwa dummy yokonzekera (placebo). Odwalawo kapena madokotala omwe amawawerenga amawadziwa omwe akulandira mankhwala enieni komanso omwe amalandira malowa mpaka phunziroli litatha.
M'maphunziro awiri omwe amachititsa kuti anthu asamayende bwino, malo opangira nicotine amapezeka kuti ndi abwino kuposa placebo pofuna kuchepetsa kupweteka kwa zilonda zam'mimba.
Mwamwayi, zotsatirapo za gulu la nicotine zinali zachilendo ndipo zinaphatikizapo kunyoza, kumutu, ndi mutu. Phunzirani ophunzira omwe sanasutepo konse atapeza zotsatira zake makamaka kukhumudwitsa.
Phunziro lina, anthu omwe ali ndi zilonda zam'mimba zowumana omwe sankachitapo kanthu pakamwa ndi mankhwala amlomo anapatsidwa mankhwala osokoneza bongo ndi ma mesamine enemas. Kuphatikizidwa kwatsopano kumeneku kunapangitsa kuti athandizidwe mu 12 mwa ophunzira 15 omwe amaphunzira.
Nicotine saoneka ngati yopindulitsa monga chithandizo chokonza; Izo sizingathandize odwala kukhala mu chikhululuko. M'malo mwake, zikuwoneka kukhala ndi zotsatira zabwino pa matenda opatsirana ( zovuta ).
Pofuna kuteteza zotsatira zoyipa kuchokera pachigambachi, ofufuza akupanga njira zotulutsira chikonga mwachindunji ku colon. Mu phunziro limodzi, capsule ya nicotine inalengedwa kuti ichite molunjika pa coloni kwa maola 6.
Kodi Zonsezi Zikutanthauzanji kwa Anthu Amene Ali ndi Ulcerative Colitis?
Zomwe zimachititsa kuti chikonga cha chilonda cha zilonda zam'mimba chiziwoneka bwino, sichidziwikiratu, koma chimapereka chitsogozo cholandira chithandizo cha mankhwala atsopano. Monga momwe ntchito ya chikonga imaonekera bwino, odwala omwe ali ndi zilonda zam'mimba tsiku lina amapindula ndi mankhwala atsopano okhudzana ndi zotsatirazi.
Zotsatira:
Green JT, Evans BK, Rhodes J, et al. "Kulankhula kwa m'kamwa kwa chikonga kuti amasulidwe ndi kuyamwa mu colon: chitukuko chake ndi pharmacokinetics." Br J Clin Pharmacol October 1999; 48: 485-493. 28 May 2009.
Mahid SS, Minor KS, Stromberg AJ, Galandiuk S. "Kusuta ndi kusuta fodya m'bwana kumagwirizana ndi kukula kwa matenda opatsirana." Inflamm Bowel Dis Apr 2007 13; 431-438. 28 May 2009.
Pullan RD, Rhodes J, Ganesh S, et al. "Kutumiza chikonga cha matenda opatsirana ndi zilonda zam'mimba." N Eng J J Mar Mar 1994; 330: 811-815. 28 May 2009.
Sandborn WJ, Wade WJ, Offord KP, et al. Kutsekemera kwa nikotini kwa chiwopsezo chochepa kwambiri. "Mayesero olamuliridwa ndi anthu osadziwika bwino, omwe ali awiri, osayenerera." Ann Intern Med Mar 1997; 126: 364-371. 28 May 2009.
Sandler RS, Sandler DP, McDonnell CW, Wurzelmann JI. "Kutengeka kwa ana ndi utsi wa fodya komanso chiopsezo cha ulcerative colitis." Am J Epidemiol Mar 1992; 135: 603-608. 28 May 2009.