Mphamvu popanda Steroids
Psoriasis ndi chizolowezi chofala cha khungu chomwe chimasintha moyo wa maselo a khungu, zomwe zimapangitsa maselo kukula mofulumira pamwamba pa khungu lako. Maselo owonjezera a khungu amapanga mamba wandiweyani, sikelo ndi zowopsya, zowuma, zofiira zofiira zomwe nthawi zina zimapweteka. Psoriasis ndi matenda osatha ( osatha ). Nthawi zina zizindikiro zanu za psoriasis zimakhala bwino nthawi ndi nthawi pamene psoriasis yanu ikufalikira.
Kuchiza kwa Malo Ovuta
Cholinga chachikulu cha mankhwala a psoriasis ndi kuleka maselo a khungu kuti asamakula mwamsanga. Ngakhale palibe mankhwala, psoriasis mankhwala angathandize kwambiri.
Koma apa pali vuto: Muyenera kuchiza psoriasis m'dera limene mphamvu zam'mwamba za steroid zingakhale zovuta, koma zoopsa za corticosteroids sizigwira ntchito. Kodi muyenera kuchita chiyani? Njira yosavuta yothetsera ndi kugwiritsa ntchito mankhwala osagwiritsa ntchito steroid. Komabe, zambiri mwa izi, monga Dovonex (calcipotriene) kapena Psoriatec (anthralin) zimakhala zovuta kwambiri kuti zigwiritse ntchito pa khungu lakuda kapena maso.
Kuti athetse yankho lanu, dokotala wanu angayang'ane kunja kwa mndandanda wa mankhwala a psoriasis omwe amavomerezedwa ndi Food and Drug Administration (FDA) ndikugwiritsa ntchito mankhwala omwe amagwiritsidwa ntchito ndi FDA-kuvomerezedwa kwa chisangalalo. Izi zikuphatikizapo Protopic (tacrolimus) ndi Elidel (pimecrolimus). Kugwiritsira ntchito mankhwala ovomerezeka chifukwa cha kugwiritsidwa ntchito kosavomerezeka kumatchedwa "off-label" ntchito ndipo sikuti ndilamulo mwangwiro, ndizofala kwambiri mu dermatology practice.
Zosintha
Mafuta (tacrolimus) ndi mafuta omwe angakhale othandizira psoriasis a nkhope ndi kubuula. Ali mu kalasi ya mankhwala omwe amatchedwa topical calcineurin inhibitors omwe amathandiza kuchepetsa kutupa ndi mapulaneti. Zomwe zingatheke komanso zotsatira zachilendo za Protopic ndizoti ngati mumamwa mowa, malo omwe mumagwiritsa ntchito akhoza kukhala ofiira ndi otentha.
Zotsatira zoyipa za Protopic zikuphatikizapo:
- Kuwotcha, kununkha, kupweteka, kufiira, kapena kumangirira m'madera omwe amagwiritsidwa ntchito
- Kumamva kutentha kapena kuzizira kuposa momwe munkachitira m'madera omwe amagwiritsidwa ntchito
- Kuyabwa
- Zikodzo
- Mapuloteni opaka tsitsi
- Mutu
- Ululu mmbuyo kapena minofu yanu
- Kuthamanga kapena mphuno yonyansa
- Zizindikiro zofanana ndi ziphuphu
- Nausea
Ngati mukukumana ndi zotsatirazi zomwe zimagwiritsidwa ntchito komanso zimakhala zovuta kapena musapite, kambiranani ndi dokotala wanu.
Zotsatira zoyipa za Protopic zikuphatikizapo:
- Zilonda zozizira
- Mphuno kapena nkhuku
- Kutupa kwa glands
- Rash
- Matenda a khungu, omwe angaphatikizepo kuthamanga, kuthamanga, kapena kutumphuka
- Kutupa kwa manja anu, mikono, miyendo, mabowo, kapena mapazi
Ngati mukukumana ndi zotsatira zoopsazi pamene mukugwiritsa ntchito Protopic, pitani kuchipatala mwamsanga.
Elidel
Elidel (pimecrolimus) ndi wina wodalirika wa calcineurin inhibitor umene umagwira ntchito ngati Protopic, koma mafuta ake osakaniza ndi ochepetsetsa ndipo mwinamwake amakhala omasuka (ngakhale sangakhale othandiza kwa psoriasis). Mofanana ndi Proptic, imathandizanso kuti malo opatsiranawo akhale ofiira kapena otentha mukamwa mowa.
Zotsatira zofanana za Elidel zikuphatikizapo:
- Kupsa, kuluma, kupweteka, kufiira, kapena kutentha m'madera omwe amagwiritsidwa ntchito
- Nkhondo kapena mabomba
- Kukhumudwa kwa diso, ngati kugwiritsidwa ntchito pafupi ndi maso anu
- Mutu
- Kukuda
- Stuffy kapena mphuno yothamanga
- Osasunthika
- Kutsekula m'mimba
- Ululu pa nthawi ya kusamba
Ngati mukukumana ndi zotsatira zowawa zomwe zimakhalapo ndipo ali ovuta kapena osachoka, kambiranani ndi dokotala wanu. Muyeneranso kulankhula ndi dokotala ngati muli ndi moto, kupweteka, kupweteka, kufiira, kapena kutentha m'madera omwe mwagwiritsira ntchito Elidel kwa oposa sabata.
Zotsatira zoyipa za Elidel zikuphatikizapo:
- Chofiira kapena pakhosi
- Fever
- Mikoko
- Kutulutsa khutu kapena ululu
- Zizindikiro zofanana ndi ziphuphu
- Kuyabwa
- Kuthamanga kwatsopano kapena kuwonjezeka
- Zovuta kumeza kapena kupuma
- Kutupa kwa lilime lanu, mmero, nkhope, milomo, maso, manja, mabowo, mapazi, kapena miyendo yochepa
- Zilonda zozizira
- Mphuno kapena nkhuku
- Kutupa ntchentche m'khosi mwanu
- Matenda a khungu, omwe angaphatikizepo kuthamanga, kuthamanga, kapena kutumphuka
Aitaneni dokotala nthawi yomweyo ngati mukukumana ndi mavuto ena akuluakulu pamene mukugwiritsa ntchito Elidel.
Chenjezo la Black Box
Zaka zingapo atatulutsidwa, Protopic ndi Elidel analandira chenjezo la " black box " chifukwa pali kugwirizana komwe kulipo pakati pa kugwiritsira ntchito ndi kukhazikitsa khansa ya khungu kapena lymphoma. Komabe, kafukufuku wotsatira sanapeze umboni wokwanira wothandizira izi zogwirizana. Kafukufuku wopitilirapo akuchitidwa, koma pakalipano, American Academy of Dermatology ndi ena adasankha kuti palibe umboni wakuti mankhwalawa amachititsa khansara komanso kuti ali otetezeka komanso ogwiritsidwa ntchito moyenera.
Mankhwala Osokoneza Bongo ndi Inshuwalansi
Kaya mumagwiritsira ntchito mankhwalawa kapena ayi, ndibwino kuti inu ndi dermatologist muzipanga pamodzi. Nthaŵi zina, makampani a inshuwalansi sakufuna kubisa kugwiritsa ntchito mankhwala okwera mtengo ngati steroid zotsika mtengo zilipo. Komabe, kalata yochokera kwa dermatologist yomwe imasonyeza kufunika kokhala ndi mankhwala osagwiritsa ntchito steroid muzochitika zina zingapangitse mankhwalawa kuvomerezedwa.
> Zotsatira:
> Feldman SR. Kuchiza kwa Psoriasis mwa Anthu Achikulire. Zaposachedwa. Idasinthidwa pa November 21, 2017.
> Chipatala cha Mayo Clinic. Psoriasis. Chipatala cha Mayo. Kusinthidwa pa March 6, 2018.
> MedlinePlus. Pimecrolimus Topical. Laibulale ya National National Medicine. Kusinthidwa pa March 15, 2016.
> MedlinePlus. Tacrolimus Topical. Laibulale ya National National Medicine. Idasinthidwa pa February 15, 2016.
> Siegfried EC, Jaworski JC, Hebert AA. Matenda a Calcineurin Inhibitors ndi Lymphoma Risk: Kusintha kwa Umboni Ndi Zomwe Zimakhudza Tsiku Lililonse. American Journal of Clinical Dermatology . 2013; 14 (3): 163-178. lembani: 10.1007 / s40257-013-0020-1.