Kafukufuku Akusonyeza Kuti ndi Matenda Odzidzimutsa
Vogt-Koyanagi-Harada syndrome (VKH) matenda ali ndi ubongo, maso, khutu, ndi zizindikiro za khungu. Kafukufuku amasonyeza kuti mwina chifukwa cha thupi lomwe limakhala ndi thupi lomwe lili ndi maselo abwino omwe ali ndi melanin ya pigment. Matenda a VKH safupikitsa moyo, koma kusintha kwa diso ndi khungu kumatha.
Sidziwika kuti matenda a Vogt-Koyanagi-Harada amapezeka bwanji padziko lonse lapansi.
Zimapezeka kawirikawiri mwa anthu a ku Asiya, Amwenye Achimerika, Latin America, kapena Middle East omwe ali nawo. Lipoti lofalitsidwa la VKH syndrome limasonyeza kuti limapezeka kawirikawiri mwa amayi komanso kuposa amuna, ndipo zizindikiro zake zingayambe pa msinkhu uliwonse.
Zizindikiro
Pambuyo pa matenda a Vogt-Koyanagi-Harada ayamba, anthu ambiri amakhala ndi zizindikiro monga mutu, viti, ndodo, khosi lolimba, kusanza , ndi kutentha thupi kwa masiku angapo. Zizindikirozi sizowona za VKH syndrome ndipo zimapezeka ngati matenda a tizilombo kapena fuluwenza . Chimene chimasiyanitsa VKH syndrome kuchokera ku "chimfine" ndicho kuyamba kwa zizindikiro za maso monga masomphenya odzidzimutsa, kupweteka, ndi kuzindikira kuunika. Kawirikawiri, VKH syndrome ili ndi magawo atatu: gawo la meningoencephalitis, gawo la ophthalmic-auditory, ndi gawo la convalescent.
M'madera a meningoencephalitis , zizindikiro monga kufooka kwa thupi, kupweteka kwa mutu, kupweteka kwa minofu mbali imodzi ya thupi (hemiparesis kapena hemiplegia), kupweteka kwapadera (dysarthria), ndi kuvutika kulankhula kapena kumvetsa chinenero (aphasia) kumachitika.
Mu gawo la ophthalmic-auditory , zizindikiro monga zozizwitsa, kupweteka, ndi kupsa mtima kwa maso chifukwa cha kutupa kwa iris (iridocyclitis) ndi uvea (uveitis) zimachitika. Zizindikiro zokhudzana ndi zolembera zimaphatikizapo kumvetserani, kumvetsera (tinnitus), kapena chizungulire.
Mu gawo la convalescent , zizindikiro za zikopa monga zowala kapena zoyera za mtundu wa tsitsi, tsitsi, kapena eyelashes (poizoni), kuwala koyera kapena khungu koyera (vitiligo), ndi kutayika tsitsi (alopecia).
Zizindikiro za khungu zimayamba masabata kapena miyezi ingapo masomphenya ndi zizindikiro zimayamba.
Kudziwa
Chifukwa chakuti matenda a Vogt-Koyanagi-Harada sapezeka, kafukufuku woyenera nthawi zambiri amafunsana ndi akatswiri. Palibe njira yeniyeni yothetsera matenda, kotero matendawa amachokera ku zizindikiro zomwe zilipo pamodzi ndi zotsatira za mayesero. Katswiri wa zamagulu adzachita pulogalamu yapamwamba kuti ayese cerebrospinal fluid (CSF) kuti asinthe maonekedwe a VKH syndrome. Katswiri wamagetsi adzayesa mwapadera maso kuti ayang'ane uveitis. Dermatologist idzatengera chitsanzo cha khungu (biopsy) pafupi mwezi umodzi pambuyo pa zizindikiro za maso zimayamba kuyang'ana kusintha kwa chikhalidwe cha VKH syndrome, monga kusowa kwa pigment (melanin) poyera kapena khungu loyera la khungu lomwe lilipo.
The American Uveitis Society imalimbikitsa kuti 3 mwa izi 4 izi zithetsedwe kutsimikizira kuti matenda a Vogt-Koyanagi-Harada akupezeka:
- iridocyclitis m'maso onse, ndi uveitis
- zizindikiro za ubongo kapena khalidwe likusintha mu CSF
- zizindikiro za khungu za poliosis, vitiligo, kapena alopecia
Chithandizo
Pofuna kuchepetsa kutupa m'maso, corticosteroids monga prednisone amaperekedwa. Ngati izi sizikuyenda bwino, mankhwala osokoneza bongo monga azathioprine (Imuran) kapena cyclophosphamide (Cytoxan, Neosar) angagwiritsidwe ntchito.
Zizindikiro za khungu zimatengedwa momwe njira ya vitiligo imathandizira, zomwe zimaphatikizapo phototherapy, corticosteroids, kapena mafuta odzozera.
Matenda oyambirira ndi matenda a matenda a Vogt-Koyanagi-Harada amathandiza kupeĊµa masomphenya osatha monga glaucoma ndi khansa. Kusintha kwa khungu kungakhale kosatha, ngakhale mwachipatala, koma kumvetsera kumabweretsedwanso mwa anthu ambiri.
> Zotsatira:
Choczaj-Kukula, A. (2005). Matenda a Vogt-Koyanagi-Harada. eMedicine, imapezeka pa http://www.emedicine.com/derm/topic739.htm
Werengani, RW (2003). American Uveitis Society: Matenda a Vogt-Koyanagi-Harada.