Mmene Kutetezera Maganizo Kumakhudzira Maganizo A Magazi
Monga momwe timvetsetsa biology pambuyo pa kuvutika maganizo ndi zokhudzana ndi chikhalidwe chakhalapo, zinthu zambiri zomwe zimaganiziridwa kuti zangokhala zokhudzana ndi maganizo tsopano zikudziwika kuti zikugwirizana kwambiri ndi kusintha kwa chilengedwe mu ubongo. Chotsatira chake, chithandizo cha kuvutika maganizo chikudalira kwambiri mankhwala osokoneza bongo omwe apangidwa kuti athetsere kuchuluka kwa mankhwala ena mu dongosolo lamanjenje.
Mankhwala ambiri amagwiritsidwa ntchito pofuna kuthana ndi kuvutika maganizo powonjezera kuchuluka kwa serotonin kapena dopamine yomwe ilipo m'thupi. Mankhwalawa amavomereza mmene maselo amkati amalankhulana, komanso amathandizira kukambirana pakati pa zigawo zosiyanasiyana za ubongo. Mankhwala otsika a serotonin ndi dopamine agwirizanitsidwa ndi kusintha kwa maganizo, ndi mankhwala oponderezedwa apangidwa kuti aziwonjezera kuchuluka kwa mankhwalawa.
Kodi Ndi Ntchito Yanji Yomwe Matenda Okhala ndi Matenda Okhudzana ndi Matenda Okhudzana ndi Matenda Okhudzana ndi Matenda Okhudzana ndi Matenda Okhudzana ndi Matenda Okhudzana ndi Matenda?
Serotonin ndi dopamine zimakhala ndi maudindo ofunika kwambiri m'madera ambiri a thupi kunja kwa ubongo, ndipo mankhwala oponderezana amagwiritsidwa ntchito kwambiri kuti athetse mavuto osiyanasiyana monga kupweteka kosatha. Madzi onsewa amadziwika kuti amakhudza mtima ndi mitsempha ya magazi.
Mu mankhwala opatsirana, dopamine amagwiritsidwa ntchito monga mankhwala ofulumira kuwonjezera (kuwonjezera) kukakamizidwa kwa magazi panthawi ya opaleshoni ndipo pamene zikhalidwe zina - monga matenda a thupi lonse - zimayambitsa kutsika kwa magazi kuposa momwe thupi limatha kuwongolera.
Pang'onopang'ono, serotonin ali ndi mphamvu yofanana ya magazi-kuonjezera zotsatira ndipo ingawonjezere momwe mtima ndi zotengera zimakhudzira mtima wa dopamine.
Kodi Chisamaliro cha Anthu Omwe Amatsutsidwa Ndi Otani?
Ngakhale kuti matenda ochepetsa matenda oterewa sapangitsa serotonin ndi dopamine kukhala ovuta kwambiri, ntchito yawo yadziwika kuti imayambitsa magazi.
Matenda omwe amachititsa kuti magazi aziwonjezeka ndi awa:
- Venlafaxine (Effexor XR)
- Monoamine oxidase inhibitors
- Tricyclic zowonongeka
- Fluoxetine (mwachitsanzo, Prozac, Sarafem)
Kuwonjezeka kwa serotonin ndi dopamine kumathandiza kwambiri momwe mankhwalawa amathandizira kuthamanga kwa magazi, koma mwinamwake pali zambiri ku nkhaniyo, ndipo njira zeniyeni zimakalibe nkhani yotsutsana. Masiku ano, kuganiza kuti mankhwalawa amachititsa kuti ntchito zonsezi zikhale zovuta kwambiri, zomwe zingapangitse zizindikiro zina (monga omwe amachititsa kuti magazi aziponderezedwa) zomwe zimatumiza thupi lonse.
Ndifunikanso kuzindikira kuti kuvutika maganizo kumagwirizanitsidwa ndi kutsika kwa magazi (komanso nkhawa zomwe zimagwirizana ndi kuthamanga kwa magazi). Choncho, pokonza vutoli, ndiye kuti kuthamanga kwa magazi kungakhale "normalize" pamapeto pake, omwe anthu ena amatha kukhala otsika kwambiri kapena ochepa.
Kuwongolera Magazi ndi Kugwiritsa Ntchito Mankhwala
Ngati muli ndi kuthamanga kwa magazi, mukhoza kugwiritsa ntchito mankhwala opatsirana pogonana. Dokotala wanu angasankhe kupewa mitundu yambiri ya mankhwala opatsirana pogonana, ndipo ayenera kuyang'anitsitsa kuthamanga kwa magazi mosamalitsa panthawi yoyamba ya mankhwala.
Anthu ambiri omwe ali ndi kuthamanga kwa magazi amatha kugwiritsa ntchito mankhwala opatsirana kwambiri omwe alibe vuto, koma ena angafunike kusintha kusintha kwapopopeni.
Kwa odwala omwe amafunika kupanikizika, kupeza mankhwala abwino - kapena kuphatikiza mankhwala - kungakhale njira yowonongeka. Cholinga cha ndondomeko iliyonse ya chithandizo ndizopindulitsa kwambiri kuposa zoopsa kapena zotsatirapo. Ngati mankhwala omwe sakukuthandizani, pali zambiri zomwe mungathe. Kuyankhulana momasuka ndi kulankhulana bwino ndi dokotala wanu ndikofunika.
Zotsatira
Brent D, et al. Kupititsa kwa SSRI kapena venlafaxine kapena popanda chithandizo chamaganizo kwa achinyamata omwe ali ndi vuto la SSRI: vuto la TORDIA loyendetsedwa mosavuta. JAMA. 2008 Feb 27; 299 (8): 901-13.
Linder AE, Diaz J, Ni W, Szasz T, Burnett R, Watts SW. Vuto la reactivity, kuthamanga kwa 5-HT, ndi kuthamanga kwa magazi mu serotonin wonyamula galimoto kota. Am J Physiol Mtima Circ Physiol. 2008 Apr; 294 (4): H1745-52. Epub 2008 Feb 8.