Mwachidule cha Theophylline Medication for Asthma

Chimene Mukuyenera Kudziwa ndi Kuyang'anira Ngati muli pa Theophylline

Theophylline ndi methylxanthine yomwe ili ndi bronchodilator ndipo ikhoza kukhala ndi zotsatira zochepa zotsutsa zotupa. Ngakhale kuti angagwiritsidwe ntchito ngati njira yothandizira, mankhwala osakaniza ndi steroid yosakanizidwa , izi siziri mankhwala osakondera pamene mphumu yosafuna imakhala ndi mankhwala ena oyenera kuti azitha kulamulira mphumu. Theophylline nthawi zambiri imakhala yotchuka kwambiri ndipo kenako savomerezedwa ndi madokotala akuchiza mphumu.

Komabe, chimodzi mwa ubwino wake waukulu poyerekeza ndi mankhwala ena onse a mphumu ndi wotsika mtengo. Izi zimapangitsa kuti zikhale zokopa kwambiri ngati mankhwala owonjezereka pambuyo pa steroid yosakanizidwa sizitha kulamulira zizindikiro za mphumu m'maganizo mwa odwala ambiri.

Chifukwa theophylline ikhoza kutha kwa maola 24, madokotala ena amagwiritsa ntchito theophylline kuti athetse vuto la chifuwa cha mphumu usiku, makamaka kwa mphumu yosalekeza yosalekeza kapena yosalekeza .

Momwe Theophylline Amagwirira Ntchito

Theophylline ndi mankhwala olamulira omwe amagwira ntchito ngati bronchodilator ndipo amachititsa kuti minofu ikhale yolimba monga gawo la mphumu yako. Theophylline imakhalanso ndi anti-inflammatory and bronchoprotective properties zomwe mwina zikhoza kufotokoza kuthekera kwake kuthandizira kuthetsa zizindikiro za mphumu kusiyana ndi zomwe zimayambitsa matendawa.

Chifukwa cha njira zotetezeka monga mankhwala opatsirana steroids (ndipo madokotala mu maphunziro masiku ano ali ndi zochepa zochepa ndi mankhwala monga momwe takhala tikuchitira nthawi yomwe anthu sakufuna), agonists omwe amatenga nthawi yaitali (LABAs) ndi leukotriene dokotala, theophylline samakonda kuuzidwa ngati mzere woyamba kapena mankhwala achiwiri a asthma ndi dokotala wanu.

Chifukwa chomwe theophylline sichikukondwera ndikuti sizimawoneka kugwira ntchito komanso mankhwala ena a mphumu. Zofukufuku sizinawonetse kuti theophylline ndi ofanana ndi mavitamini otetezedwa mu mankhwala ochizira mphumu. Mofananamo, kafukufuku wasonyeza kuti LABA ndi othandiza poonjezera mankhwala achiwiri poonjezera theophylline.

Theophylline imafuna magawo ena a magazi kuti akwaniritsidwe kuti akhale ndi zotsatira zochiritsira komanso ingayambitse mavuto aakulu pamene msinkhu uwu wadutsa. Madokotala nthawi zambiri amafotokoza izi ngati njira zochepetsetsa zochiritsira.

Theophylline imagulitsidwa pansi pa mayina awa:

• Elixophyllin
• Theo-24
• Theo-Bid Duracap
• TheoCap
• Theochron
• Theo-Dur
• Theo-Dur Kuwaza
• Theolair
• Theovent LA
• Slo Bid
• Slo-Phyllin
• Uniphyl

Kuwunika Theophylline Minga

Kuphatikiza pa zotsatira zake, chinthu chimodzi omwe odwala sakonda kugwiritsa ntchito theophylline ndi kuti mumayenera kutenga magazi kuti muyang'ane mayendedwe a theophylline m'magazi anu. Malingana ndi momwe mukuchitira, mungafunikire kuchita izi kamodzi pamwezi mpaka mutakwaniritsa kafukufuku wathanzi, wothandiza wa theophylline m'magazi anu. Kawirikawiri, dokotala akuyesera kupeza theophylline mu magazi a 5-15 μg / ml. Ngati nthenda yanu ya theophylline ili pamwambapa, mumakhala ndi mwayi waukulu.

Kuwonjezera pamenepo, ndikofunika kulola dokotala wina yemwe mumamuwona akudziwa kuti muli pa theophylline. Chifukwa chakuti theophylline imagwirizana ndi mitundu yambiri ya mankhwala, dokotala aliyense yemwe mumamuwona akufunikira kudziwa kuti muli pa theophylline. Kafukufuku wasonyeza kuti odwala 35 peresenti ya theophylline amalembedwa mankhwala ena omwe amatsutsana kwambiri ndi theophylline.

Mankhwala ena omwe amagwirizana ndi theophylline ndi awa:

• Allopurinol: Akhoza kuchulukitsa magazi a theophylline
• Benzodiazepines: Theophylline ikhoza kuchepa
• Beta-Blockers : Angachepetsenso bropalatation zotsatira za theophylline
• Carbamazepine: Theophylline ikhoza kuchepetsa kuchuluka kwa magazi ndi kuonjezera ngozi yowopsa
• Ciprofloxacin: Matenda a Theophylline akuwonjezeka ndi mankhwalawa ndi ma antibayotiki ena m'kalasi ili. Ngati mukulandira IV theophylline ndi IV piprofloxacin kudzera mumzere wofanana wa IV, khunguli
• Formoterol: Theophylline imapangitsa kuti pakhale potassium
• Zafirlukast: Theophylline ikhoza kuchepetsa magulu a magazi a zafirlukast

• Zileutoni: Zingathe kuwonjezereka ndondomeko ya theophylline ya seramu

Komanso, ngati muli ndi mavuto ena azachipatala kapena zinthu zomwe muyenera kusamala ngati mutatenga theophylline:

• Matenda a chiwindi: Ngati muli ndi vuto la chiwindi thupi lanu silinayanjanitse theophylline mofulumira ngati munthu wamba, ndipo mlingo wanu uyenera kuchepa.
• Kusweka mtima kwa mtima: Msoti umafunika kuchepa ngati matenda a chiwindi
• Kusuta: Ngati mumasuta, mungafunike mlingo wapamwamba wa theophylline. Komanso, ngati mutasuta kusuta fodya mungadwale kuchepetsa dozi ya theophylline.

Zizindikiro Zamakono Kwa Theophylline

Pali malo ambiri omwe theophylline amagwiritsidwa ntchito masiku ano pochiza mphumu:

1. Monga mankhwala opatsirana pogwiritsira ntchito steroids sizitha kuyambitsa zizindikiro za mphumu kapena pamene zina zowonjezereka ( LABAs) kapena ( leukotriene modifiers) ndizosawathandiza kuthetsa zizindikiro.
2. Monga chithandizo chamakono chachikulu pamene wodwala samamatira (kapena ndi chovuta kapena chovuta) kwa steroid yosakanizidwa ndi leukotriene kusintha sizothandiza.
3. Pamene wodwalayo ali mu chipatala chachikulu chomwe chimakhala ndi vuto lalikulu la mphumu komanso osayankha mankhwala ena.

Theophylline Mbali Zotsatira

Chimodzi mwa zifukwa zazikulu zomwe theophylline sichigwiritsidwanso ntchito ndi chifukwa cha zotsatirapo. Odwala ambiri sakhala ndi zotsatirapo pa theophylline. Odwala ena amakhalanso ndi zotsatira zoyipa pa sabata yoyamba ya mankhwala ndi theophylline. Ngati mungathe kulekerera poyamba, thupi lanu likhoza kukhala lolekerera. Zizindikiro zomwe thupi lanu lidzazolowereka, koma muyenera kulankhula ndi adokotala ngati sakuchoka, kuphatikizapo:

• Kusokonezeka m'mimba kapena kupweteka
• Kutsekula m'mimba
• Mutu
• Kusagona
• Kukhumudwa
• Kupuma

Zotsatira zoopsa kwambiri zomwe muyenera kuzidziwitsa dokotala wanu mwamsanga ndi awa:

• Mtima wosayenerera umagunda
• Kugonjetsa
• Kuthamanga kwa khungu
• Kuthamanga

_Zotsatira:

_{Pashko S, Simons WR, Sena MM, ML Stoddard. Mlingo wa mankhwala a theophylline. Clin Ther. 1994-Nov-Dec; 16 (6): 1068-77.}

> UpToDate. Theophylline: Kudziwa mankhwala osokoneza bongo

_{National Heart, Lung, ndi Blood Institute. Report of Panel Panel 3 (EPR3): Malangizo Othandizira Kuzindikira ndi Kusamalira Khunyu}