Mavitamini a Angieotensin (ACE) ndi omwe amachititsa chitetezo cha matenda a mtima (CHF), zomwe zimapangitsa kuti mtima usapse magazi okwanira ku ziwalo.
Momwe Amagwirira Ntchito
Pogwiritsidwa ntchito bwino kwa zaka zoposa 20, ACE inhibitors amalepheretsa CHF kuyenda m'njira zitatu:
- Zimaphimba mavitamini omwe amachititsa mitsempha ya mitsempha, yomwe imachepetsa kuthamanga kwa magazi ndipo imatulutsa magazi ambiri pamtima, kuti ikhale yosavuta.
- Amachepetsa kuchuluka kwa mchere ndi madzi m'thupi, zomwe zimachepetsa kuthamanga kwa magazi.
- Amaletsa kupanga mankhwala otchedwa angiotensin, omwe amachititsa kuti zitsulo ziwongetse ndi kukweza mphamvu ya magazi.
Mitundu
ACE inhibitors, monga Vasotec ( enalapril ) ndi Capoten (captopril), amavomerezedwa kuti mtima usachepetse mwayi wopweteka mtima ndi kupwetekedwa.
Kwa zaka zambiri, mankhwala othandizira mankhwala a mtima - kuyendera ACE inhibitors ndi angiotensin II receptor blockers (ARBs) - ndiyo njira yokondweretsedwa. Koma nkhani ya 2007 ku American Diabetes Association ya DOC News inatsimikizira kuti akazi, makamaka, amapindula kwambiri ndi ARBs. Pambuyo pake, phunziro lapadera la 2008 ku New England Journal of Medicine linatsimikizira kuti mphamvu za ACE zogwira ntchito bwino, ndipo ma ARB amakhalabe mwayi kwa ena.
Zotsatira Zachimake ndi Kuyanjana kwa Mankhwala
Poyamba, odwala akhoza kuuzidwa kutenga mankhwalawa pogona kuti athe kuchepetsa chizungulire choyamba chifukwa cha kuchepa kwa magazi.
Zovuta zina zomwe zimagwiritsidwa ntchito ndizo:
- Kupitiriza, chifuwa chouma
- Kufooka, chizungulire
- Kukhumudwa m'mimba, kusala kudya
- Kuphulika khungu
- Metallic kukoma m'kamwa
- Mpweya waukulu wa potaziyamu
- Nausea ndi mutu
Zovuta Zowonjezera
Zotsatira zowawa zambiri zimaphatikizapo mantha, malungo, kuzizira, kutupa kwa nkhope komanso mimba yowawa.
Uzani dokotala wanu ngati mukukumana ndi zina mwa izi, koma musasiye kumwa mankhwalawa nokha. Ma ARB monga Cozaar (losartan) angaperekedwe kwa odwala omwe amakhudzidwa kwambiri ndi ACE inhibitors.
Azimayi omwe ali ndi pakati kapena akuyamwitsa, kapena omwe akukonzekera kutenga pakati, sayenera kutenga ACE inhibitors. Komanso, ngati muli ndi matenda a shuga , lupus, kapena mtima, impso kapena chiwindi, kapena ngati mwakhala mukudwala matenda amtima kapena posachedwa kugwedeza impso, dokotala wanu safuna kulamula ACE inhibitors.
Kuphatikiza ziwalo za ACE ndi mowa zingayambitse kuopsa kwa magazi. Zina zowonjezera mankhwala ndi mankhwala, kuphatikizapo diuretics (mapiritsi a madzi) ndi mankhwala omwe ali ndi potassium, angasokonezenso zochita za ACE inhibitors. Onetsetsani kuti dokotala yemwe amalemba mankhwala anu a ACE ali ndi mndandanda wathunthu wa mankhwala ena onse.
Zotsatira:
"ACE Inhibitors: Summary of Recommendations." consumerreports.org. 2008. Consumers Union.
"Angiotensin-Kutembenuza Enzyme (ACE) Inhibitors." kandimachi.biz. Jul 2007. Texas Institute Institute.
Ofufuza Oweruza a Pulezidenti. "Angiotensin-Kutembenuza - Kutetezedwa kwa Enzyme mu Stable Coronary Artery Disease." New England Journal of Medicine 351: 20 (2004): 2058-68.
Chilamulo, Bridget Murray. "ARBs Outperform ACE Zizindikiro za Akazi Ndi Mtima Olephera." DOC News 4:11 (2007): 10. American Association ya shuga.
"Mankhwala Amene Amagwiritsidwa Ntchito Kowopsa Mtima." americanheart.org . 9 Jan. 2008. American Heart Association.
Scow, Dean Thomas, Ellen G. Smith, ndi Allen F. Shaughnessy. "Njira Yophatikizana ndi ACE Inhibitors ndi Angiotensin-Receptor Blockers mu Mtima Woperewera." American Physician Physician 68: 9 (2003): 1795-98. 4 Nov. 2008..
Ofufuza Ofufuza. "Telmisartan, Ramipril, kapena Onse Odwala Pachiopsezo Chokwanira pa Zochitika Zosautsa." New England Journal of Medicine 358: 15 (2008): 1547-59. 4 Nov. 2008.