Zimene Mukuyenera Kudziwa Ponena za Kukoma Kofunikira
Anthu ambiri amada nkhaŵa akamachita mantha kuti mwina angakhale chizindikiro cha matenda a Parkinson. Komabe, palinso chifukwa china chofala chomwe chimadziwika kuti chivomezi chofunika kwambiri (ET), ndipo chiribe vuto lalikulu la Parkinson . Ndipotu, ET imakhala yowonjezera kawiri monga matenda a Parkinson, ndipo, mosiyana ndi Parkinson, sichikuchititsa kuti munthu asakhalenso wosakhazikika, wosagwedezeka kapena wovutika maganizo .
Palibenso vuto la kugwilitsika maganizo kwaumtima.
Ngakhale kuti zingakhale zotsitsimutsa kumva kuti kutentha kwanu sikuli chifukwa cha matenda a Parkinson, sizikutanthauza kuti kunjenjemera sikukukhumudwitsa. Kwa anthu ena, kunjenjemera kwakukulu kumabwera ndipo kumapita ndipo kumawavutitsa kwambiri. Kwa ena, kunjenjemera kwakukulu n'koipa kwambiri kuti kumanga nsapato kapena kudya ndi ziwiya n'zosatheka.
Kuzindikira Kufunika Kwambiri
Mosiyana ndi kuponderezedwa kwa Parkinsonian, kunjenjemera kwakukulu nthawi zambiri (koma osati nthawi zonse) kumbali zonse - ndiko kuti, kumakhudza mbali zonse panthaŵi imodzi. Manja amayamba kukhala mbali yambiri ya thupi, ngakhale mutu ukhoza kukhala nawo mbali. Kusiyana kosiyana ndi Parkinson ndikuti kutentha kumakhala koipitsitsa pamene manja akugwiritsidwa ntchito mmalo mwa nthawi yopuma.
Zina mwazinthu zikuphatikizapo mbiri yakale ya banja. Kuwopsya kwakukulu nthawi zambiri kumatengera mwambo wa autosomal, kutanthauza kuti ngati muli nawo, muli ndi mwayi wokhalapo mmodzi wa makolo anu.
Chinthu chinanso chochititsa chidwi chochititsa mantha ndi chakuti nthawi zambiri amatha kumwa mowa pang'ono.
Kodi Zimakhala Zotani Zofunika Kwambiri?
Pafupifupi anthu mamiliyoni 10 a ku America ali ndi mantha aakulu, oposa 5 peresenti ya anthu onse ku United States. Monga kusintha kwakukulu kwa thanzi, kutengeka kwakukulu kumawonjezeka pamene tikukula.
Kutenthedwa kumawonjezeka mu kukula kwake, kumakhala kwakukulu ndi koonekera kwambiri ndi nthawi. Ikhoza kufalikiranso ku zigawo zina za thupi.
Kodi N'chiyani Chimachititsa Kuti Anthu Azikhala Okhumudwa?
Mbali za ubongo zomwe zimayendetsa kayendetsedwe ka kayendetsedwe zimakhala ngati zigawo zosiyana za oimba. Gawo lirilonse liri ndi nyimbo yake, yomwe nthawi zambiri imakhala mogwirizana ndi mbali zina. Chizindikiro cha kunjenjemera kwakukulu kumakhala mofulumira monga chibadwa chachibadwa chomwe chimapangidwa ndi thalamus ndi mtima wochepa wa olivary wa ubongo, zomwe zonse zimadziwika kuti zimakhudzidwa ndi kuyenda. Maderawa ndi othandizira pa PET kuyang'ana panthawi yamantha.
Sindikuwonekeratu chifukwa chake maderawa akhoza kugwira ntchito molakwika. Ngakhale kuti nthawi zambiri mabanja amakhala ndi mbiri yowopsya kwa anthu okhala ndi ET, palibe majini omwe amadziwika bwino. Anthu ena asonyeza kuti zinthu zina zachilengedwe, monga mankhwala ena omwe amapezeka mu nyama yophika bwino, akhoza kukhala nawo. Palibe mgwirizano womwe wapezeka ndi mankhwala ophera tizilombo kapena mankhwala ophera tizilombo toyambitsa matenda.
Kodi N'chiyani Chimachititsa Kuti Mukhale Wovuta Kwambiri?
Kuwonjezera pakukula, chivomezi chachikulu chikhoza kuvulazidwa ndi zinthu zomwe tingakhale nazo tsiku ndi tsiku. Kutopa , kusinthasintha kwa kutentha, kupsinjika maganizo, komanso ngakhale kusintha kwakukulu komwe mukugona kumene kungasinthe kuopsa kwa mantha.
Palinso mankhwala osiyanasiyana omwe amachititsa mantha kwambiri, monga omwe amagwira ntchito pakati pa mitsempha monga anti-depressants, Reglan , lithium, ndi mowa, komanso zowonjezera monga caffeine, bronchodilators kapena cocaine. Steroids ikhoza kuwonjezereka kwambiri, monga momwe mahomoni a chithokomiro angathere. Ndipotu, pali mankhwala osiyana kwambiri omwe angabweretse mantha kwambiri, ndibwino kuti mutangomvetsera mwamsanga nthawi imene mukugwedezeka, ndikudziŵa bwino zotsatira za mankhwala alionse omwe mukuwatenga.
Kodi Katswiri wa Neuro Angatani Kuti Ndizitsimikizira Kuti Ndine Woopsa Si Matenda a Parkinson?
Kawirikawiri, kungoyankhula ndi iwe ndikuyang'ana kuntchito kwanu kudzakhala kokwanira kwa katswiri wa sayansi ya zamoyo kuti adziŵe mantha aakulu.
Nthawi zina zimatenga nthawi kuti mukhale otsimikiza. Kutentha kwakukulu kumapangitsa kusintha pang'onopang'ono kusiyana ndi matenda a Parkinson.
Muzovuta zovuta, DaTscan imayesedwa kuti ayang'ane ndi nigra, yomwe ndi mbali za ubongo zomwe zagonjetsedwa mu matenda a Parkinson. Kufufuza uku kumagwiritsa ntchito radioisotope kuyang'ana ntchito ya basal ganglia. Phokoso lofunika kwambiri, kujambulidwa kudzakhala koyenera.
Kodi Kutentha Kumakhala Kofunika Motani?
Pali njira zambiri zothetsera mantha. Malingana ndi momwe kuwopsyezera kwakukulu, njira yabwino ingakhale yopanda chithandizo chamankhwala nkomwe. Popeza mankhwala onse amabwera chifukwa chowopsa, ngati kutentha sikukuvutitsa, ndiye kuti palibe chifukwa chokhala ndi mankhwala kapena mankhwala ena.
Komabe, ngati kuwopsya kukuyenda m'njira ya tsiku ndi tsiku, ndiye kuti mankhwala, monga propranolol kapena primidone, angakhale othandiza. Ngati izi sizigwira ntchito, mankhwala ena akhoza kuyesedwa, kuphatikizapo jekeseni wa Botox chifukwa cha mutu kapena kunjenjemera kwa mawu. Pa milandu yovuta kwambiri, njira zopangira opaleshoni, monga kukakamiza kwambiri ubongo, zingaganizidwe.
Pamene chiwombankhanga chofunikira chingakhale chokhumudwitsa, sikuli kuopseza moyo. Ngati zizindikiro zikukulepheretsani kuchita zinthu zomwe mukufuna kapena muyenera kuchita, muyenera kulankhula ndi dokotala wodziwa bwino njira yabwino yothetsera zizindikiro zanu.
Zotsatira
ED Louis, Zheng W, Jurewicz EC, Watcher D, Chen J, Factor-Litvak P, Parides M. Kuphulika kwa magazi a beta-carboline alkaloids m'nthabwala yofunikira. Neurology. 2002 Dec 24; 59 (12): 1940-4.
ED Louis, Agnew A, Gillman A, Gerbin M, Mphesa AS.Kuyerekezera kuchuluka kwa chaka cha kuchepa: zomwe zingachitike, zomwe zimachitika nthawi yaitali zowonjezereka pazitsulo zolimba kwambiri m'magulu awiri ofunika kwambiri .J Neurol Neurosurg Psychiatry. 2011 Jul; 82 (7): 761-5. Epub 2011 Mar 24.
Kathleen Poston, Zowonongeka za Common Movement Disorders, Continuum: Kusokonezeka kwa Mavuto 16, Nambala 1, February 2010