Kufufuza Avastin ndi Zovuta Zake
Avastin (bevacizumab) ndi mankhwala omwe amamwa mtundu wa mapuloteni (VEGF) omwe amapezeka m'matumbo ambiri. Pochita zimenezi, zimathandiza kupewa zotupa kuti zifalitsidwe kumalo ena m'thupi ( metastasizing ).
Kafukufuku wina wasonyeza kuti kuwonjezera Avastin ku chemotherapy regimen kungathandize anthu omwe ali ndi khansa yapamwamba kwambiri amakhala moyo wautali. Komabe, wopanga Avastin wapereka machenjezo okhudza zoopsa zina zogwirizana ndi mankhwalawa, ndipo kafukufuku wofalitsidwa mu Annals wa Pharmacotherapy anafotokoza zotsatira zina zomwe zingayambitse - impso kulephera.
Zambiri za Phunziro
Ndikofunika kuzindikira kuti phunziroli ndilopoti, zomwe zikutanthauza kuti zinayankhula za munthu mmodzi. Mwapadera, mwana wamwamuna wazaka 26 yemwe ali ndi khansa yosaoneka bwino yomwe imakhala ndi khansa yambiri imayambitsa matenda a impso pamene akugwiriridwa ndi Avastin ndipo ochita kafukufuku anaganiza kuti Avastin adayambitsa.
Zotsatira za lipotili sizimasonyeza kuti anthu omwe amatenga Avastin amafunika kudandaula za kukula kwa impso. Ndikudutsa mfundoyi pokhapokha ngati wina atenga zochitika za Avastin zizindikiro za impso zolephera, choncho akhoza kuika awiri ndi awiri mofulumira. Zizindikiro zimatha kuphatikizapo kusungunuka kwa magazi, kuthamanga kwa magazi, kusagwirizana kwa mtima, kusokonezeka kwa minofu, ndi kugwidwa.
Zofanana Zowonjezera Zowonjezereka
- Avastin Amalimbikitsa Kukula kwa Khansara ya Colon
- FOLFOX4 Plus Avastin: Ndikofunika Kuyesera?
- Kodi FOLFOX4 Kwa Inu?
- FOLFOX4 Kugwiritsa Ntchito Mankhwala Ogwiritsira Ntchito Mankhwala Osokoneza Bongo
Mankhwala Ena a Khansa Yoyamba
Kuonjezera pa Avastin, mankhwala omwe amagwiritsira ntchito makamaka khansa yowopsa kwambiri, palinso mankhwala ena omwe amapezeka pa matendawa.
Zindikirani, chithandizo chapadera cha matenda oyipa kwambiri chimadalira kukula kapena siteji ya matenda.
Nazi njira zina zomwe zimapangidwira:
- Kuchotsa opaleshoni (resection) ya chotupacho, gawo lomwe lakhudzidwa ndi matumbo, kukhetsa maselo a mitsempha ndi ziwalo za ziwalo zogwirizanitsa;
- mankhwala ochizira kapena chemotherapy, kuphatikizapo mankhwala monga 5-FU, capecitabine, ndi leucovorin;
- radiotherapy kwa anthu okhala ndi khansara ya rectal;
- kuyang'anitsitsa pakapita opaleshoni, chemotherapy, ndi njira zina zothandizira kuti khansayo isabwerere.
Mwamwayi, m'zaka 30 zapitazo, kumvetsa kwathu za khansa yoyipa yakula bwino. Ife tsopano tikudziwa zambiri za khansara iyi ya pathogenesis, zomwe zimayambitsa, ndi zifukwa zomwe zingayambitse chiopsezo. Komanso, tsopano tikumvetsa bwino momwe tingawonetsere matendawa ndi kupewa matenda aakulu. Kuwonjezera pamenepo, gulu la mankhwala ali muipiyi kuti athetse matenda oyambirirawa, ndipo njira zosiyanasiyana zimapititsira patsogolo chithandizo cha matendawa. Poyembekezera, akatswiri akuyembekeza kuti chithandizo cha matenda oopsachi chidzangowonjezereka. Komabe, njira yabwino yothetsera khansara yaikulu ndi kuigwira mwamsanga pogwiritsa ntchito njira zowunikira monga colonoscopy.
Gwero: Barakat, R. ndi Singh, N. "Njira zamakono za Nephritis kwa Bevacizumab Kuchiza mu Metastatic Leiomyosarcoma." The Annals of Pharmacotherapy 41.4 (2007): 707-710. Inapezeka pa 21 Apr 2007.