Chemotherapy yotentha ndi njira yowonekera kwa anthu omwe ali ndi khansa yowonongeka kapena yowonongeka. Mwachidziwitso, njirayi imatchedwa optoticuction opereshoni (CRS) ndi hyperthermic intraperitoneal chemotherapy (HIPEC). Zimagwirizanitsa opaleshoni ya m'mimba ndi operethrapiyoni yokha kuti iwononge khansa yanu m'njira zosiyanasiyana nthawi imodzi.
Kodi Wopempherera HIPEC ndi ndani?
Njira ya HIPEC imagwiritsidwa ntchito pochiza mitundu yambiri ya khansa yamtunduwu kuphatikizapo yofiira, yamimba, yovunda , mesothelioma , ndi yowonjezera.
Si chithandizo cha kutsogolo kapena chithandizo cha kusankha kwa wina yemwe watulukira kumene ali ndi khansa yosagwiritsa ntchito mthupi. Ngati mukuganiza za HIPEC, msinkhu wanu, thanzi lanu lonse, komanso chofunika kwambiri, siteji ndi kalasi ya khansa yanu ndi zomwe zimathandiza dokotala kudziwa ngati chithandizochi chili choyenera kwa inu.
Gawo 1: Kupanga Opaleshoni
Musanalandire HIPEC, dokotala wanu adzachita opaleshoni kuchotsa zotupa zonse zooneka m'mimba mwathu. Adzachotsanso ziwalo zilizonse zolimbana ndi matenda, monga matumbo aang'ono, kapangidwe, kapena mazira. Dokotalayo amatha kuchotsa kapena kutentha ziwalo zochepa kuchokera ku ziwalo zofunika (zomwe sizingakhoze kuchotsedwa), monga chiwindi, panthawi ino. Ngakhale mutakhala ndi kachilombo koyambitsa matenda a khansa m'mbuyomo, mufunika CRS kuti mupeze madalitso ochuluka kuchokera kwa HIPEC.
Gawo Lachiwiri: HIPEC Procedure
Pambuyo pa opaleshoniyo pamene mukugona pansi pa anesthesia dokotala wanu akuchita opaleshoni ya HIPEC.
Mwachidziwikire, kutanthauza "kutentha" amatanthauza "kutentha" - osati scalding, koma kutentha kuposa thupi lanu kutentha. Mankhwala a chemotherapy amasungunuka chifukwa chasonyezedwa kuti mungathe kuonjezera kugwiritsa ntchito mankhwalawa mwa kuwotcha pa nthawi yobereka.
Mawu akuti intraperitoneal amatanthauza kumene mankhwala amadzimadzi amathandizira.
Mkati mwa mimba yanu yophimbidwa ndi membrane yotetezera yotchedwa peritoneum, yomwe ili pafupi ndi malo am'mimba - malo omwe mimba yanu yonse (matumbo, chiwindi, kapangidwe) zimatsekedwa. Mankhwala a chemotherapy amalowetsedwa mu danga lino ndipo amaloledwa kusambitsa ndi kuchiwumitsa kwa maola atatu. Mankhwala amodzi omwe amagwiritsidwa ntchito pa HIPEC ndi cisplatin, omwe nthaŵi zina amaperekedwa ndi mitomycin C. Mitomycin C si mankhwala a chemotherapy, koma amagwiritsidwa ntchito kuthandiza kuchepetsa kukula kwa khansa zina, monga khansa yoyipa.
Kubwezeretsedwa kwa opaleshoni yotchedwa Cytoreduction Surgery ndi HIPEC
Iyi ndi ntchito yovuta komanso yayitali, yomwe ingakhale yotsiriza mpaka maola 14. Kudzera kwanu kudzafunika kuyang'anitsitsa mosamala kuchipatala. Pambuyo pa opaleshoniyi mumatha kukhala masiku asanu ndi asanu mu chipatala chachikulu. Pano mudzayang'anitsitsa zomwe mukuchita kuti mutha kukhazikika mwamsanga kuti mutumizidwenso ku chipatala chachipatala kuchipatala. Maofesi a chipatala amavomereza pakutsata njirayi kuyambira pa sabata kupita patangopita mwezi umodzi.
Zomwe Zingatheke za HIPEC
Monga momwe zilili ndi opaleshoni ina yaikulu, ndi kwanzeru kuganizira zoopsa zomwe zingakhalepo musanavomereze opaleshoniyi.
Mavuto akuluakulu ambiri amapezeka kuchokera ku opaleshoni yokha, yomwe ingakhale opaleshoni yaikulu. Mwinanso mungakhale ndi zovuta kuchokera m'masiku angapo a chubu kapena chakudya cha makolo, chomwe chimafunidwa pakutsata opaleshoni pamene matumbo anu amakhala. Opaleshoni ya cytoreduction imayambitsa kutaya mwazi, matenda, komanso kuthekera kwa matenda a m'mimba kapena kuthekera kwa chibayo.
HIPEC ngokhayo imakhala ndi zovuta zochepa monga mankhwala a chemotherapy, makamaka mbali yaikulu, imakhala mkati mwathu. Chifukwa cha izi, pali zotheka kuti m'mimba aziwombera poizoni. Pali zotheka kuti mankhwalawa athandizidwe pang'ono ndikuyenda m'magazi anu, koma zotsatira zake zimakhala zofanana ndi mankhwala a chemotherapy zotsatira monga:
- Kutaya tsitsi
- Kutaya mphamvu
- Kusintha kwa kukoma
- Nsowa ndi kusanza
- Kutsekula m'mimba kapena kudzimbidwa
Kodi Njirayi Ingachize Khansa Yanga?
CRS ndi HIPEC zimangoganiziridwa mwapang'onopang'ono za khansa ndipo zimakhala zowonjezera ubwino ndi kutalika kwa moyo wanu, osati monga chithandizo chochizira. Kafukufuku wasonyeza kuti njirayi ingathandizire moyo wautali, koma sikuvomerezedwa kwa aliyense. Ndipotu, palibe chopindulitsa chomwe chimapindulitsa komabe ndi njirayi.
Ambiri omwe amagwiritsa ntchito khansa amagwiritsa ntchito njirayi popitiriza kafufuzidwe monga momwe akuwonekeratu kuti ndi odalirika, koma osatetezedwa, komanso achiwawa. Musanachite opaleshoni, dokotala wanu adzafotokozera zoopsa zomwe zingakhalepo potsata ndondomekoyi, koma funsani mafunso ngati pali chirichonse chimene simukumvetsa.
Zotsatira:
Alexander, HR et al. (June 2013). Zochitika Zothandizira Kugwirizana ndi Kukhalitsa Kwanthaŵi Yaitali Pambuyo Kuchitidwa Opaleshoni Yopangidwira ndi Regional Chemotherapy kwa Odwala ndi Malignant Peritoneal Mesothelioma. Opaleshoni; 153 (6): 779-786.
Hanna, Nadar. (nd). Kupanga Opaleshoni ndi HIPEC. Pulogalamu ya University of Maryland Yovomerezeka Kwambiri; Webinar.
Khatri, Vijay. (January 2010). Kupanga Opaleshoni Yopangidwira ndi Hyperthermic Intraperitoneal Chemotherapy kwa Colorectal Khansa: Kodi Panacea Kapena Imene Imalepheretsa Odwala? Journal of Clinical Oncology; 28 (1): 5-7.