Pamene Ikubwera ED, Ndikofunika Kupsinja ndi Kuwuzani
Kusokonekera kwa Erectile kumakhudza anthu 22% mwa amuna oposa 40 ku United States. Popeza pali anthu pafupifupi 64 miliyoni oposa 40 ku US, izo zikutanthauza kuti pafupi 14 miliyoni mwa iwo amavutika kupeza erection.
Erectile Dysfunction Drugs
Izi zimapangitsa kuti mankhwala osokoneza bongo a erectile akhale otere. Mankhwalawa - omwe amadziwika kuti Viagra, Cialis, ndi Levitra - amachokera ku kalasi ya mankhwala omwe amatchedwa PDE5 inhibitors.
Poyambirira kulengedwa kuti athandize odwala omwe ali ndi matenda a mtima, mankhwalawa anali ndi zotsatira zina zomwe zinapindula kwambiri kuposa ntchito yawo yoyambirira.
Vuto la PDE5 zowonongeka ndi chizoloŵezi chawo choyanjana ndi mankhwala ena omwe amachititsa zomwezo mu thupi. Nitrates (nitroglycerin ndi yowonjezereka) imayambitsa mitsempha ya magazi kuwonjezera - kukula kwa kukula ndi kunyamula magazi ambiri osatsutsa. Nitrates amathandiza minofu yamtima kugwira ntchito molimbika pamene kulola magazi ambiri ku minofu ya minofu, kutanthauza kuti odwala omwe ali ndi vuto la chifuwa cha mtima (angina) angatenge nitroglycerin kuti apweteke.
PDE5 inhibitors amagwira ntchito mofananamo. Mwatsoka, mukasakaniza PDE5 inhibitors ndi nitroglycerin, zotsatira zake zingatheke kawiri kapena katatu ndipo zimayambitsa kugwa koopsa mwadzidzidzi m'magazi . Kuphatikizidwa kwa mitundu iwiri ya mankhwala ndi owopsa, American Heart Association ikusonyeza kuti odwala sayenera kutenga nitroglycerin mkati mwa maola 24 atatenga PDE5.
Musanayambe kutenga PDE5 inhibitor, muyenera kukambirana ndi dokotala kuti mumvetsetse mgwirizano pakati pa mankhwalawa ndi mankhwala ena omwe mungakhale nawo.
Kuwululidwa Kwathunthu
Kumvetsetsa momwe magulu awiriwa akugwiritsira ntchito mankhwala ndi ofunika ngakhale kwa amuna omwe samatenga nitrates.
Ndakhala ndikukuuzani kuti muyenera kuitanitsa 911 kuti muwapweteke pachifuwa . Ngati mutenga pulojekiti ya PDE5 mukakhala ndi kupweteka pachifuwa, muyenera kuwuza anthu omwe akuyankha mofulumira.
Thandizo lachidziwitso lachidziwitso cha kupweteka kwa chifuwa cha mtima zimapereka kupereka nitroglycerin pomwepo. Musanapereke mankhwala aliwonse, othandizira opaleshoni ndi ena othandizira zaumoyo amaphunzitsidwa kufunsa za chifuwa cha mankhwala. Iwo amafunikanso kufunsa za PDE5 zowonongeka asanapereke nitroglycerin, koma funso limenelo ndi lovuta kufunsa ndipo ambiri omwe akuyankha sangatero.
Yankhulani
Muyenera kulankhula ngati mutenga mankhwala a erectile malingaliro, mosasamala kuti ndizosamveka kunena.
Lembani PDE5 yanu inhibitor pamndandanda wa mankhwala ngati mumasunga. Ndizotheka kuti muzisunga mankhwala kumalo osiyanasiyana kusiyana ndi mankhwala ena onse. Muyenera kukhala oyenerera ngati mukufuna kukhala otetezeka.
Si onse omwe ali ndi PDE5 omwe amavomerezedwa ndi FDA, mwina. Ndipotu, a FDA anapempha kukumbukira ma Capsules Amtundu Wathu Wogonana Wowona Amagonana ndi Amagetsi a Max Energy Supplement Men's Formula Capsules, onsewa ali ndi matembenuzidwe a PDE5 inhibitors ngakhale adalengezedwa monga zowonjezera zonse.
Ngati mukugwiritsa ntchito zowonjezerapo zomwe zimadzinenera kuti mwamuna azikuthandizani kapena mankhwala a erectile osayenerera ndiye muyenera kuwauza odwala opaleshoni.
Izo ziri kwa inu, koma ine ndikanaganiza kuti manyazi amayenera kupewa kupezeka kwa mankhwala omwe amawopsa kwambiri. Kumbukirani, pali ena 14 miliyoni kunja uko ali ndi vuto lomwelo; sizochita manyazi.
> Zotsatira:
> Laumann, EO, et al. "Kufala ndi Correlates ya Erectile Dysfunction ndi Race ndi Kusiyanasiyana pakati pa Amuna Okalamba 40 kapena Okalamba ku United States: Kuchokera Mmene Amuna Ponena za Kufufuza zaumoyo wa zachipatala." Journal of Sexual Medicine . Jan 2007 PMID: 17081223
> "FDA Akupempha Kukumbukira za 'Amunthu Amuna Ogonana Amagonana,' 'Zowonjezera Zakudya Zamagetsi'. 2 Nov 2007. FDA News. FDA. 13 Nov 2007
> Webb, DJ, ndi al. "Citrate ya Sildenafil ndi Kugwiritsa Ntchito Mankhwala Osokoneza Magazi: Zotsatira za Maphunziro Ogwiritsa Ntchito Mankhwala Osokoneza Bongo Ndi Organic Nitrate ndi Calcium Antagonist." American Journal of Cardiology. 4 Mar 1999 PMID: 10078539
> Kloner, RA "Kugonana ndi Wodwala Ndi Maganizo Okhudza Maganizo: Onetsetsani Sildenafil." The American Journal of Medicine . 18 Dec 2000 PMID: 11137498
> O'Rourke, M, ndi Jiang Xiong-Jing. "Sildenafil / Nitrate Kuyanjana." 2000. Masamba Ovomerezeka Ozungulira. AHA. 13 Nov 2007