Matenda omwe kale ankadziwika kuti pauciarticular adiopathic nyamakazi
Nyamakazi ya anyamata odwala matenda odwala matenda a nyamakazi (omwe poyamba ankatchedwa pauciarticular adiopathic arthritis kapena a pauciarthritis) ndi kachigawo kakang'ono ka nyamakazi kamene kamakhala ndi matenda osapitirira asanu. Nthenda yotchedwa Oligoarticular child's idiopathic rthritis ndiyo yodziwika kwambiri ya ana adiopathic arthritis subtype. Amakhala ndi 30% mpaka 60% mwa ana onse omwe ali ndi matenda a nyamakazi ku North America ndi Europe.
Nthendayi yamatenda a ana omwe amadziwika bwino kwambiri amadziwika kuti:
- Kulimbana ndi oligoarthritis - Palibe njira yowonjezera yowonjezera yowonjezera miyezi 6 yoyamba ndi matenda.
- Mankhwala otchedwa oligoarthritis - Kuwonjezeka kwowonjezereka kumachitika pakatha miyezi isanu ndi umodzi yodwala ndipo pamapeto pake pali ziwalo zinayi.
Pafupifupi hafu ya ana omwe ali ndi matenda a nyamakazi a mtundu wa oligoarticular amayamba zaka 4 mpaka 6 mutatha matenda. Ngakhale kuti palibe njira yeniyeni yolongosolera kuti ndi ana ati omwe angapite patsogolo kuti apange mtundu wochulukirapo, pali zizindikiro za matenda zomwe zikuwoneka kuti zikuwonjezera mwayi, kuphatikizapo kugwirizanitsa mgwirizano, mawonekedwe kapena mchiuno (kapena bulu ndi mkono), ndi mlingo wamakono wa erythrocyte m'madzi 6 oyambirira.
Makhalidwe Achizindikiro ndi Zizindikiro
Chiwerengero cha msinkhu wa ana omwe ali ndi matenda a nyamakazi a ana a zaka 2 mpaka 4 ku Caucasus anachokera ku United States ndi Europe.
Atsikana amavutika kwambiri kuposa anyamata (3 mpaka 1). Kuyamba kwa mwana wamwamuna yemwe ali ndi zaka makumi asanu ndi zisanu (5) zakale (5) zakale (5) zaka khumi ndi zisanu (5) zaka khumi ndi zisanu ndi ziwiri (5) zaka zisanu ndi ziwiri (5) zaka zisanu ndi ziwiri (7) zaka khumi ndi zisanu ndi ziwiri (5) zaka zisanu ndi ziwiri (7) zaka zisanu ndi ziwiri (7) zaka zisanu ndi ziwiri (7) zakale zapitazo zimakhala zosawerengeka.
Kawirikawiri, poyambitsa matenda a nyamakazi a ana aamuna omwe ali ndi matenda a oligoarticular, amakhala ndi mbali yowonjezera yomwe imakhudza chiwalo chimodzi kapena ziwiri zikuluzikulu.
Bondo ndilo gawo lofala kwambiri. Chikopa, mkono, ndi chiwerengero ndizotsatira zomwe zimagwiritsidwa ntchito. Zizindikiro zodabwitsa (mwachitsanzo, malungo, kuthamanga) ndizosazolowereka, monga kuthandizira kwa m'chiuno ndi kumbuyo. Ngati mwana ali ndi kachilombo ka HIV kapena kubwezeretsa, chiwerengero choyambiranso chikuwonetsedwa ndikuyang'aniranso za matendawa.
Ngakhale mutha kuyembekezera kupweteka kukhala chizindikiro choyambirira kwambiri cha amtundu wa ana omwe amadziwika kuti oligoarticular adiopathic arthritis, amayamba kuwonekera kwambiri. M kholo angazindikire kuti mwana wawo ali ndi vuto, kusayenerera kuyenda kapena kuthamanga, kapena kutupa kwa ophatikizidwawo.
Pafupifupi 70% mpaka 80% a ana okhala ndi oligoarticular ana adiopathic arthritis ndi 80% mpaka 95% ali ndi mafuta ochulukirapo a ana odwala matenda a nyamakazi omwe ali ndi nyamakazi. Maina a ANA amakhala otsika kwambiri. M'madera a ANA odwala omwe ali ndi mafupa amtundu wa ana, amakhala ndi chiopsezo chachikulu chotenga uveitis . Komanso, ana ambiri omwe ali ndi mafuta a oligoarticular adiopathic arthritis ali ndi kachilombo koyambirira kapena kowonongeka ka CRP , mlingo wa maselo oyera a magazi, ndi kuchepa kwa magazi (wofatsa).
Ponena za uveitis, pali mayesero a ma laboratory omwe amathandiza kutsimikizira kuopsa kwake kwa anterior uveitis kwa ana omwe ali ndi oligoarticular ana adiopathic arthritis.
Mayesero sakuneneratu kuyambika, komabe. Mayesowa angaphatikizepo mlingo wa a2-globulin mu seramu, komanso HLA antigen (HLA-A19, HLA-B22, HLA-DR9).
Kuchiza kwa Amuna Oligoarticular Idiopathic Arthritis
Mankhwalawa amathandiza kuti mwana asatulukidwe ndi matenda a nyamakazi. Kufananako mu chithandizo ndi chifukwa cha kulowerera kwachisawawa .
Kuti mupitirize kukhala oligoarticular ana adiopathic arthritis, njira yowonjezera ikugwiritsidwa ntchito:
- Chithandizo ndi NSAID (kapena popanda injata ya intra-articular steroid)
- Methotrexate ayesedwa ngati ayankhidwa ndi intra-articular steroid jekeseni sikwanira
- TNF inhibitor ikhoza kuwonjezeredwa, kapena popanda methotrexate, ngati methotrexate yokha isakwanire
Azulfidine (sulfasalazine) ndi Plaquenil (hydroxychloroquine) angagwiritsidwe ntchito pamodzi ngati njira ina. Chikhululukiro (kaya chosasamala kapena chokwanira) cha ana a oligoarticular adiopathic nyamakazi amatha kupindula mu 60-70% a ana oligoarticular ana adiopathic nyamakazi ogwiritsa ntchito methotrexate.
Zotsatira:
Kelley's Textbook ya Rheumatology. Elsevier. Kusindikiza kwachisanu ndi chinayi. Chaputala 107. Chithandizo cha Amuna Amuna Amadzi Amadzi. Hsu, Lee, Sandborg.
Oligoarticular ana adiopathic arthritis. Zaposachedwa. Pamela F. Weiss MD. 12/09/15.
http://www.uptodate.com/contents/oligoarticular-juvenile-idiopathicararritis
OrthoInfo. Matenda a Amuna. September 2013.
http://orthoinfo.aaos.org/topic.cfm?topic=a00075
Zolemba zoyambirira za njira yovuta ya uveitis mu oligoarticular ana adiopathic arthritis. Zulian E. et al. Journal of Rheumatology. November 2002.
http://www.ncbi.nlm.nih.gov/pubmed/12415607