Provera ndi hormone yomwe imateteza chiberekero komanso imayambitsa kusamba
Provera angapangidwe chifukwa cha zifukwa zingapo, kawirikawiri kuchiza msambo waukulu kapena kusiya nthawi (amenorrhea) zomwe zimayambitsa vuto lalikulu la mahomoni. Provera (medroxyprogesterone) ndi mawonekedwe a progesterone -hormone yomwe imapangidwa pambuyo pa kutsekemera (pamene dzira limatulutsidwa kuchokera ku ovary).
Kuonjezera apo, Provera nthawi zina amagwirizanitsidwa ndi estrogen kuti azitsatira zizindikiro zokhudzana ndi matenda a mthupi (mwachitsanzo, kutentha kwambiri) kwa amayi omwe amachititsa chiberekero omwe ali ndi chiberekero.
Pachifukwa ichi, cholinga cha Provera ndikuteteza kukulitsa kwa chiberekero cha uterine, chomwe chingayambitse khansa ya uterine. Provera ingagwiritsidwenso ntchito mu test test progesterone.
Provera ndi Amenorrhea
Mimba yam'mimba yachiwiri imachitika pamene mayi amasiya kukhala ndi nthawi yokwanira kwa miyezi itatu (pamene ankakhala nthawi zonse) kapena kuposa miyezi isanu ndi umodzi (ngati kale sizinali zachilendo). Pali zifukwa zingapo zomwe zingayambitse mankhwalawa omwe akuphatikizapo:
- Mimba
- Matenda a chithokomiro
- Matenda a Polycystic ovarian
- Mbali yapamwamba ya prolactin
- Hypothalamic amenorrhea: vuto limene lingayambe chifukwa cha kupanikizika, kupweteka kwambiri, kapena kuchita masewera olimbitsa thupi
Pofuna kupeza chifukwa cha kachilombo kawiri ka mayi, dokotala adzalamula mayesero angapo ngati mayeso a mimba, mahomoni a magazi, komanso mayeso a progesterone (omwe amatchedwanso kuti progesterone withdrawal test).
Mu test test progesterone, mayi akhoza kuuzidwa Programu 5 milligrams kapena 10 milligrams kwa masiku asanu ndi asanu kapena khumi kuti awone ngati ali ndi magazi m'mimba.
Ngati mkazi samachiza m'mimba mkati mwa masabata awiri atatenga Provera, ndiye kuti ali ndi mawere otsika kwambiri m'thupi mwake kapena ali ndi vuto lakutuluka, monga matenda a Asherman.
Ngati mkazi ali ndi magazi m'mimba (omwe nthawi zambiri amapezeka masiku atatu mpaka asanu akuletsa Provera) ndiye kuti ali ndi estrogen yokwanira mu thupi lake, motero amchere ake sakhala ovulating (otchedwa anovulation).
Pachifukwa ichi, adokotala adzayesa zowonjezera kuti adziwe chifukwa chake akudzola.
Pulogalamu ya Provera ndi Kuperewera kwachiberekero kosaoneka bwino
Ngati mkazi ali ndi matenda odzoza thupi, akhoza kuyamba kutuluka mwazi wamadzimadzi osasinthasintha. Vuto lokhala ndi matenda odwala matendawa ndikuti akhoza kutengera chiberekero cha uterine, chotchedwa endometrial hyperplasia , chomwe chingayambe kukhala khansa ya uterine.
Matenda a Polycystic ovary (PCOS) ndi chitsanzo choyambirira cha vuto limene nthawi zambiri limayambitsa kusakhazikika kwa msambo kuchokera ku matenda aakulu. Matenda a polycystic ovary ndi omwe amavuta kwambiri azimayi otha msinkhu. Zizindikiro ziwiri za PCOS ndi nthawi zosasinthasintha komanso zapamwamba zamtundu wina (monga testosterone), zomwe zimathandiza kuti chitukuko cha acne ndi hirsutism chikule bwino. Matenda amadzimadzi monga kunenepa kwambiri ndi insulini kukana amakhalanso wamba mu PCOS.
Kawirikawiri, kuphatikizapo estrogen-progesin njira ya kulera (mwachitsanzo, "pilisi") imalimbikitsidwa kwa amayi omwe ali ndi PCOS, kuti azisamalira nthawi ya kumaliseche kwa amayi, ateteze chiberekero cha amayi, ndipo athandizidwe ndi kukhala ndi ma chitsanzo, acne).
Kwa amayi omwe sangathe kutenga kapena kusankha kuti asagwiritse ntchito njira yothandizira njira yogonana ndi estrogen-progesin, Provera ndi mwayi.
Provera amagwira ntchito popewera minofu yambiri mu uterine.
Provera ndi Hormone Replacement Therapy
Provera angagwiritsiridwenso ntchito pamodzi ndi estrogen mwa amayi omwe amatha kupha amayi omwe ali ndi chiberekero. Kugwiritsidwa kwa estrogen ndi progesterone kumatchedwa hormone replacement therapy ndipo cholinga chake ndi kuyeretsa zizindikiro zokhudzana ndi kusamba kwa thupi monga kutentha kwa moto.
Cholinga cha progesterone kuwonjezera pa estrogen ndiko kuteteza chiberekero. Ichi ndi chifukwa chake progesterone imaperekedwa kwa amayi omwe ali ndi chiberekero. Kaya Provera kapena progesterone yachilengedwe (yowonjezera) imayikidwa.
Mankhwala opatsirana amadzimadzi azitsulo ayenera kugwiritsa ntchito pa mlingo wotsika kwambiri komanso nthawi yochepa kwambiri, podziwa kuti chiopsezo cha amayi ndi phindu la kutenga mankhwala opatsirana pogwiritsa ntchito ma hormone ayesedwa bwinobwino.
Kuwonjezera apo, ndibwino kukumbukira kuti magazi alionse m'mayi omwe ali ndi chiberekero ndi chiberekero ayenera kuyesedwa kuti athetse khansa.
Zimene Tingayembekezere Kuchokera Pogwiritsa Ntchito Provera
Popeza Provera ndi hormone, ikhoza kuchititsa zotsatira. Zofala kwambiri ndi kupweteka kwa mutu, kunyozetsa, kutentha kwa m'mawere, ndi kusintha kwa maganizo. Zotsatirazi zimayenera kudutsa masiku angapo mutatenga Provera.
Zotsatira zina zingaphatikizepo:
- Sinthani kutuluka m'mimba kapena kutuluka
- Zikodzo
- Kuwonjezera kulemera
- Kutopa kapena mavuto ogona
Ndikofunika kuzindikira kuti Provera amatsutsana ndi mimba, choncho onetsetsani kuti mumamuuza dokotala ngati mukuganiza kuti mungakhale ndi pakati. Nthawi zina dokotala wanu amafuna kuti mutengepo magazi kapena mkodzo woyembekezera kutenga mimba musanayambe kumwa mankhwalawa.
Kuonjezera apo, Provera palokha si njira zodalirika za kulera, ngakhale kuti ndi hormone. Ngati mukugwiritsa ntchito Provera, onetsetsani kuti mukugwiritsa ntchito njira yothetsera kulera (mwachitsanzo, kondomu) kuti muteteze mimba.
Bweretsani mavuto anu azachipatala ndi mankhwala ndi dokotala musanatenge Provera. Kuwonjezera pa kutenga pakati, palinso zina zotsutsana ndi kutenga Provera kuwonjezera pa zotsatira zake, makamaka ngati ziphatikizidwa ndi estrogen.
Mawu Ochokera
Cholinga chodziwika kwambiri chofotokozera Provera ndi kuthandiza dokotala kuganizira kapena kuthana ndi vuto lakumwezi monga kutaya thupi kwachilendo kapena kusowa kwa nthawi. Amagwiritsidwanso ntchito popeweratu chiberekero cha amayi omwe akutsatira mchitidwe wa uterine. Zingakhale zomveka kumvetsetsa chifukwa chake mukutenga hormone, monga Provera. Onetsetsani kuti mubweretse mafunso kapena zodandaula ndi dokotala wanu.
> Zotsatira:
> Kaunitz AM. Kusamalira Kuchetsa Kwambiri kwa Uterine. Mu: UpToDate, Barbieri RL (Ed), UpToDate, Waltham, M
> Ndefo UA, Eaton A, Green MR. Polycystic Ovary Syndrome: Kubwereza kwa Njira Zothandizira Mwachindunji pa Njira Zamaphunziro Achipatala. Pharmacy ndi Therapeutics. 2013 Jun; 38 (6): 336-338, 348, 355.
> Provera (Medroxyprogesterone Acetate). Pfizer. https://www.pfizer.com/products/product-detail/provera.
> Wokoma MG, Madsen KP. Kuwunika ndi Kuyendetsa Kuphulika kwachiberekero kosayembekezereka kwa amayi a Premenopausal. American Family Physician. 2012 Jan 1; 85 (1): 35-43.