Mchere wochuluka wa hypertonic saline ndi imodzi mwa njira zatsopano zothandizira mankhwala a cystic fibrosis (CF). Ofufuza ena a ku Australia adapeza ubwino wa salin hypertonic pamene adawona kuti oyendetsa galimoto okhala ndi CF anali ndi zotsatira zabwino kuposa anthu omwe ali ndi CF omwe sanadumphe. Ofufuzawa ankakhulupirira kuti kuyendetsa mchere wamchere wa madzi m'nyanja pa nthawi yofufuzira ndi chifukwa chake oyendetsa opaleshoni anali ndi zochepa zozizira kusiyana ndi anzawo omwe sankachita nawo mantha, ndipo phunziroli linatsimikizira izi.
Ofufuzawa anafalitsa zotsatira za maphunziro awo mu 2006, ndipo kuyambira nthawi imeneyo, hypertonic saline yakhala ikupezeka ngati chithandizo cha mankhwala kwa anthu ambiri omwe ali ndi CF.
Kodi Hypertonic Saline ndi Chiyani?
Saline wamba ndi njira yamadzi ya mchere yomwe imakhala ndi mchere womwewo monga madzi athu enieni. Mchere wa hypertonic ndi madzi amchere omwe amakhala ndi mchere wambiri kuposa saline wamba, choncho mchere wochuluka kuposa mchere wathu. Njira yowonjezera ya saline ndi 0.9% mchere. The salin hypertonic yogwiritsidwa ntchito mu mankhwala a CF ndi 7% mchere.
Mankhwala a hypertonic saline amaperekedwa kwa anthu okhala ndi cystic fibrosis kawiri tsiku lililonse.
Momwe Ikugwirira Ntchito
Mavitamini amatha kutuluka mkati ndi kunja kwa maselo ndi ndondomeko yotchedwa osmosis , kumene madzi omwe ali ndi mchere wambiri amatsanulira pa membrane kuti aphatikize ndi madzi omwe ali ndi mchere wambiri. Mwachidule, chiwonongeko chimatanthauza kuti madzi amatsatira mchere.
Mu mankhwala a CF, makina otchedwa nebulizer aerosolizes a hypertonic saline solution. Mphuno ya saline imatenthedwa ndipo ikukhazikika mumlengalenga. Chifukwa hypertonic saline imakhala ndi mchere wambiri kusiyana ndi madzi a thupi, imatulutsa madzi m'maselo kupita kumtunda. Madzi amasakanikirana ndi mthunzi wandiweyani pamtunda, kuupangitsa kukhala wochepetseka komanso kosavuta kutsokomola kapena kutsogoloza.
(Kulongosola ndi mankhwala achipatala kuti akhudze ntchentche.)
Kafufuzidwe kafukufuku wogwiritsa ntchito hypertonic saline kwa anthu omwe ali ndi cystic fibrosis akusonyeza kuti mankhwalawa angapangitse kusintha kochepa mu mapangidwe a pulmona ndi zovuta kapena zovuta zochepa. Komabe, zotsatira za chithandizo zimasiyana pakati pa anthu, ndipo anthu ena amatha kupeza chithandizo chambiri kuposa ena.
Zotsatira Zoipa
Mankhwala a hypertonic saline si mankhwala, koma amachititsa kusintha thupi lomwe lingakhale ndi zotsatira zosasangalatsa. Anthu ena pogwiritsa ntchito hypertonic saline awonjezeka kukhwima, kupweteka kapena kupweteka pachifuwa chifukwa cha kukhumudwa kwa minofu.
Si Saline Madzi Amchere Okha? Kodi Zingapangidwe Kunyumba?
Ayi. Mchere wambiri uyenera kukhala weniyeni, ndipo izi zikanakhala zovuta kukwaniritsa njira yokha. Chofunika kwambiri, yankholo liyenera kukhala lopanda kanthu kuti tipewe mabakiteriya omwe angapangitse moyo ku airways.
Zotsatira:
> Chetnut MS, Prendergast TJ. Kusokonezeka kwazitsulo. Mu: Papadakis MA, McPhee SJ, Rabow MW. eds. Kuzindikira Zamankhwala Zamakono ndi Chithandizo 2016 . New York, NY: Hill ya McGraw; 2016.
Donaldson, SH, ndi al. "Mucus Clearance ndi Mapungidwe a Mphuno mu Cystic Fibrosis ndi Hypertonic Saline". 2006. New England Journal of Medicine 354 (3): 1848-1851. 4 August 2008.