Enzyme imeneyi yaphunzitsidwa kuti igwiritsidwe ntchito pochizira matenda a zilonda zam'mimba
Mwachidule
Bromelain ndi mapuloteni a proteolytic omwe amachokera ku tsinde ndi madzi a chinanazi. Choyamba chinapezedwa kumapeto kwa zaka za m'ma 1800, koma sichinagwiritsidwe ntchito ngati chakudya chodyera mpaka zaka za m'ma 1950. Bromelain ndi wotsutsa-kutupa ndipo wagwiritsidwa ntchito monga chithandizo chamagazi ndi magazi owonda, komanso kuchitira zovulaza masewera, sinusitis, nyamakazi, ndi kutupa.
Bromelain akuphunziranso kuti azigwiritsidwa ntchito monga mankhwala othandizira matenda opatsirana (IBD) , makamaka ulcerative colitis.
Ntchito
Bromelain amadya mapuloteni, chifukwa chake amagwiritsidwanso ntchito monga tenderizer ya nyama. Monga chowonjezera, chimapezeka ngati capsules kapena mapiritsi. Monga chithandizo chamagazi, mlingo woyenera ndi mlingo wa 500 mg katatu patsiku. Zingatengedwe ndi chakudya, koma zimathandiza kuchepetsa kutupa pamene zimatengedwa m'mimba yopanda kanthu. Bromelain amavomerezedwa ku Germany kuti agwiritsidwe ntchito pambuyo pa opaleshoni, pamene mlingo umachokera ku 80 mpaka 320 mg patsiku. Mlingo woyenera wa ntchito zina, monga kuchiza nyamakazi, sikudziwika. Bromelain nthawi zambiri amatengedwa masiku 8 mpaka 10.
Bromelain ndi odana ndi yotupa, koma palibe kafukufuku wambiri wosamalira ntchito yake mu Crohn's disease kapena ulcerative colitis. Pali nkhani ya odwala awiri omwe ali ndi ulcerative colitis omwe amavomereza bwino mankhwala ndi bromelain.
Bromelain sanaphunzirepo ndi anthu omwe ali ndi IBD, koma pali phunziro limodzi lomwe linkachitidwa pamatumbo omwe amachotsedwa m'mimba mwa anthu omwe ali ndi matenda a Crohn ndi matenda a ulcerative. Mitunduyi inkaoneka ngati ikuyankhidwa bwino ndi bromelain, ndipo inasonyeza zolemba zochepa za IBD kuposa minofu yomwe sinkagwiritsidwe ndi bromelain.
Kudya zipatso zambiri za chinanazi sizingapereke zotsatira zofanana ndi kutenga bromelain supplement. Bromelain amapezeka makamaka mu tsinde la chinanazi, zomwe sizimadya.
Kugwiritsa Ntchito Mankhwala ndi Kuwonjezera
Bromelain amatha kuwonjezera mphamvu ya antibiotics, kuphatikizapo amoxicillin. Zitha kukhala ndi zotsatira zofanana ndi tetracycline, koma kafukufuku wamakono pa izi akutsutsana.
Bromelain imakhalanso ndi zotsatira pamagazi, ndipo imakhudza mphamvu ya magazi kuti iphimbe . Choncho, sayenera kuthandizidwa ndi mankhwala kapena mankhwala owonjezera omwe amawombetsa magazi kapena omwe amachititsa kuti magazi asaphedwe, kuphatikizapo:
- Coumadin (warfarin)
- Adyo
- Ginkgo biloba
- Heparin
- Non-steroidal anti-inflammatories (NSAIDs), kuphatikizapo aspirin , ibuprofen , ndi naproxen
- Plavix (clopidogrel)
- Anawona palmetto
Bromelain nayenso akhoza kuonjezera zotsatira zomwe zimakhala zosautsa pa thupi. Izi zikuphatikizapo mankhwala osokoneza bongo omwe amagwiritsidwa ntchito ngati osokoneza bongo komanso omwe amakhala pansi. Zitsanzo zina ndi izi:
- Mowa
- Anticonvulsants, kuphatikizapo Dilantin (phenytoin) kapena Depakote (valproic acid)
- Mabala a barbiturates, kuphatikizapo phenobarbital
- Benzodiazepines, kuphatikizapo Ativan (lorazepam), Xanax (alprazolam) ndi Valium (diazepam)
- Catnip
- Kava Kava
- Mankhwala osokoneza bongo, kuphatikizapo codeine
- Anthu ogona, kuphatikizapo Ambien (zolpidem) , Lunesta (eszopiclone) , Rozerem (ramelteon) , ndi Sonata (zaleplon)
- Tricyclic zodetsa nkhawa, kuphatikizapo Elavil (amitriptyline)
- Valerian
Zotsatira Zotsatira
Monga ndi mankhwala aliwonse kapena othandizira, nthawi zonse amakhala ndi mwayi wotsutsa. Bromelain ayenera kupewa ndi wina aliyense amene ali ndi zovuta zowonjezera kwa chinanazi kapena zomera zina mu Banja la Bromeliaceae.
Bromelain ingachititse mavuto, kuphatikizapo:
- Kutsekula m'mimba
- Nausea
- Kuchuluka kwa magazi kumayambiriro kapena kutuluka magazi kwachiberekero
- Kuwonjezeka kwa mtima
- Mimba imakhumudwitsidwa
- Kuthamanga
Chenjezo la Mimba
Bromelain sanaphunzire kwambiri amayi omwe ali ndi mimba kapena akuyamwitsa.
Chifukwa bromelain ikhoza kuyambitsa magazi, sivomerezedwa kuti tigwiritsidwe ntchito ndi amayi omwe ali ndi mimba kapena akuyamwitsa. Uzani dokotala wanu ngati muli ndi pakati kapena mukuyamwitsa ndipo mwatenga kapena mukuganiza kutenga bromelain.
Mawu Ochokera
Ngakhale kuti bromelain imavomerezedwa ku ntchito zina ku Germany, pakali pano sivomerezedwa ku US kuti zithetse vuto lililonse. Umboni wogwiritsidwa ntchito mu IBD ukukwera, koma panopa siwongokwanira kulengeza ntchito yake yofala. Uzani dokotala wanu ngati mukufuna kugwiritsira ntchito bromelain, kapena ngati mukugwiritsa ntchito bromelain.
Zotsatira:
Kane S, Goldberg MJ. "Kugwiritsira ntchito bromelain kwa matenda a zilonda zam'mimba." Ann Intern Med 18 Apr 2000; 132: 680. 6 Feb 2016.
Ke F, Yadav PK, Ju LZ. "Mankhwala Osakaniza Mankhwala Opaleshoni Pachipatala cha Ulcerative Colitis." Saudi Journal of Gastroenterology: Wolemba Journal wa Saudi Gastroenterology Association . 2012; 18 (1): 3-10. 6 Feb 2016.
Onken JE, Greer PK, Calingaert B, Hale LP. "Mankhwala a Bromelain amachepetsanso kusungunuka kwa mankhwala opatsirana pogwiritsa ntchito mankhwala otchedwa cytokines ndi chemokines ndi colonic biopsies in vitro." Clin Immunol Mar 2008; 126: 345-352. 6 Feb 2016.
Tinozzi S, Venegoni A. "Zotsatira za bromelain pa seramu ndi minofu ya amoxicillin." Mankhwala Osokoneza Bongo Exptl Clin Res 1978, 4: 39-44. 6 Feb 2016.