Madokotala Amagwiritsa Ntchito Mayeso a Magazi a Procalcitonin kuti Athandizire Kuwona Zopweteka
Procalcitonin (PCT) ndi kafukufuku wamagazi omwe kaŵirikaŵiri amachitidwa ngati pali kukayikira kuti wodwalayo akhoza kukhala ndi matenda a bacterial sepsis , matenda oopsa omwe angathe kupha moyo. Kuyeza kwa procalcitonin ndi njira imodzi yothetsera vutoli mwamsanga komanso mwamsanga. sungani miyoyo.
Kutanthauzira Procalcitonin Zotsatira
Munthu wathanzi, procalcitonin sangathe kukwezedwa.
Ngati munthu akudwala, ndipo akuganiza kuti sepsis akukayikira, labu la procalcitonin lidzatengedwa kuti liwone ngati matenda alipo. Ndikofunika kuzindikira kuti procalcitonin sichidziwa mtundu wa matenda; M'malo mwake, zimasonyeza kuti matenda angathe kukhalapo. Ngati mayeso a procalcitonin ali othandiza, dokotalayo amayang'ana mayesero ena komanso kuyezetsa magazi kuti adziwe ngati ali ndi kachilombo ka HIV, komanso momwe angachitire.
Ngati sepsis akukayikira, mayesero ena, monga chikhalidwe cha magazi ndi chiwerengero chokwanira cha magazi (CBC) , kawirikawiri amachitidwa kuti adziwe ngati sepsis alipo, ndi kudziwa chomwe chimayambitsa matenda. Nthaŵi zina, procalcitonin imagwiritsidwa ntchito kusiyanitsa pakati pa matenda aakulu, monga matenda opuma, ndi matenda omwe asanduka machitidwe.
Matenda Akumidzi Akutsutsana ndi Matenda Oteteza (Sepsis)
Matenda a m'deralo ali mbali ina ya thupi; Zitsanzo zimaphatikizapo matenda opuma, matenda a dzino kapena mafupa.
Sepsis ndi matenda a systemic omwe alowa m'magazi ndipo amasamukira kumadera onse a thupi. Ngakhale kuti n'zotheka kuti kachilombo ka HIV kameneka kakuwopsyeze moyo wanu, sepsis ndizovuta kwambiri kuti zikhale zovuta komanso zowonjezereka.
Procalcitonin Zotsatira
Ngakhale zotsatira za kuyesedwa kwa procalcitonin ziyenera kutanthauziridwa ndi dokotala kapena wophunzira wina wothandizira zaumoyo, zotsatira zake kawirikawiri zimamasuliridwa motere:
- Procalcitonin ya 0 -00 μg / L imayembekezera munthu wathanzi.
- Mapulogalamu a Procalcitonin osachepera .5 μg / L angasonyeze kuti ali ndi matenda, koma msinkhu wotere sungathe kukhala matenda a systemic monga sepsis. Matenda a m'dera lanu, monga dzino lachitsulo kapena matenda opuma, angakhalepo.
- Mbali ya procalcitonin pakati pa .5 - 2 μg / L imasonyeza kuti kachilombo koyambitsa matenda kangatheke, koma sichidziwitsidwa cha sepsis.
- Mabala a Procalcitonin a 2-10 μg / L amasonyeza kuti sepsis ndiwotheka.
- Procalcitonin zotsatira za 10 μg / L kapena zazikulu zimasonyeza mwayi waukulu wa kupwetekedwa kwambiri kapena kupweteka kwapadera komanso kawirikawiri mankhwala opatsirana ndi mankhwala amodzi ndi madzi amayamba nthawi yomweyo.
Zotsatira za procalcitonin zingagwiritsidwenso ntchito kuti adziwe ngati kachilombo kawopsedwe kamayambitsa mabakiteriya kapena kachilombo. Ngati matenda amadziwika kuti alipo, ndipo chiwerengero cha procalcitonin ndi chochepa kwambiri, kupezeka kwa mabakiteriya sikungatheke, ndipo ndizotheka kuti kachilombo ka HIV kamayambitsa matendawa. Izi zingalepheretse kugwiritsa ntchito mankhwala osokoneza bongo mosayembekezereka, popeza mavairasi sathandizidwa ndi mankhwala oteteza maantibayotiki.
Zifukwa Zina za Procalcitonin Yokwera
Kuphatikiza pa kuchepa, palinso zifukwa zina zomwe munthu angakhalire ndi mkulu wa procalcitonin.
Mwachitsanzo, ana obadwa kumene, msinkhu wokhawokha m'magazi ndi wapamwamba popanda matenda omwe alipo. Kuvulala - makamaka kupsinjika kwakukulu kapena opaleshoni - kungapangitsenso zotsatira zabwino popanda kukhalapo kwapadera. Mankhwala ena, osokonezeka osati chifukwa cha sepsis, ndipo ngakhale khansara amachititsanso kukwera kwa ma procalcitonin.
Zinthu zomwe zimachepetsa mlingo wa mpweya womwe umapezeka m'thupi la thupi, mosasamala kanthu chomwe chimayambitsa, ukhoza kubweretsa procalcitonin wokwezeka pamene palibe matenda omwe alipo. Izi zimatha kuchoka chifukwa cha kuchepa kwa oxygen chifukwa cha mphumu kapena chibayo mpaka kumangidwa kwa mtima .
Makhalidwe Ochepa a Procalcitonin Ali ndi Pena Kapena Osapanda Maso
N'zotheka kwa wodwala yemwe ali ndi sepsis kuti awonetsere ndi chiwerengero chochepa chotchedwa procalcitonin. Ngati mayesowa atangoyamba kumene, matendawo akhoza kukhala otsika, koma akhoza kuwonjezeka pa maola angapo otsatira kapena masiku ochepa.
Maseŵera ochepa angathenso kupezeka pamene palibe chitsimikizo cha matendawa. Izi zikhoza kukhala choncho ngati matendawa ndi ovuta kupeza. Wodwala sangakhale ndi zizindikiro za matenda pamene mayeso amasonyeza kuti matendawa alipo.
Procalcitonin ndi Sepsis: Kodi Zonsezi Zimatanthauza Chiyani?
Kwenikweni, chiwerengero cha procalcitonin chokha chimangotanthauza kuti mtundu wa matenda ulipo. Chotsatira cha procalcitonin ndi chitsogozo, osati chidziwitso. Ganizirani zotsatira za mayesero ngati chizindikiro choti kuyeseranso kuyenera kuchitidwa, osati kugonana kwenikweni.
Odwala salandira chithandizo malinga ndi kuchuluka kwa procalcitonin mlingo wokha: chiwerengero chonse cha thanzi lawo tsopano chikuyankhidwa, ndipo mankhwala amachokera kuchipatala cha dokotala. Wodwala nthawi zonse amafufuzidwa chifukwa cha zizindikiro zina za matenda . Kwa wodwala yemwe akuyang'aniridwa kumayambiriro kwa sepsis, ndipo ali ndi chiwerengero chochepa cha procalcitonin, kubwereza mayesero panthawi ina kungasonyeze kuti sepsis ilipo.
Mtengo weniweni wa procalcitonin ndiwomwe ungapangitse kuchipatala koyambirira, zomwe zingathe kupha moyo mwamsanga. Kwa munthu amene akupanga sepsis, kupatsidwa maola angapo mofulumira chifukwa chapamwamba ya procalcitonin amatha kusiyanitsa pakati pa matenda omwe amachititsa mwamsanga mankhwala osokoneza bongo ndi matenda omwe amafunika kwambiri kuti asamalire ma intaneti .
Nthawi zina vuto la sepsis limakhala lovuta kudziwa chifukwa munthu amene ali ndi funsoli sangathe kuzindikira kuti ali ndi kachilombo ka HIV. Chinachake ngati chaching'ono ngati phazi la wothamanga chingayambitse kupuma. Kwa odwalawa omwe sadziwa kuti ali ndi kachilombo, mayeso a procalcitonin ndi othandiza makamaka.
Zotsatira:
> Chakraborty, Sutirtha. Kodi timafunikira procalcitonin kuti tipeze sepsis? Association of American for Clinical Chemistry. Webusaiti. > February > 2015.
> Jin, Ming. Procalcitonin: Akugwiritsa ntchito mu labotale yachipatala kuti azindikire za sepsis. Lab Med. 2010; 41 (3): 173-177.
National Institutes of Health. Procalcitonin zothandiza poyambitsa mankhwala opatsirana pogwiritsa ntchito odwala omwe ali ndi matenda aakulu. Webusaiti. March 2013.