Mankhwala Opweteka Pogwiritsa Ntchito Khungu Lanu - Iontophoroesis
Mukapita kuchipatala, mumatha kupatsidwa njira zothandizira . Makhalidwe apadera amasankhidwa ndi wodwala wanu ndipo amadalira zomwe zikuchitika ndi msana wanu (kapena malo ena.) Kawirikawiri, pulogalamu ya kunyumba (HEP) ndi gawo lalikulu la ndondomekoyi, koma wodwala wanu akhoza kuwonjezera zinthu monga traction, kutentha kwamtendere, ndi mitundu ina yakumverera bwino (ndi njira zosiyanasiyana zomwe zatsimikiziridwa kudzera m'maphunziro a zachipatala.) Kawirikawiri, cholinga cha njirazi ndi kuthandiza kumasuka ndi / kapena kuchititsa minofu yogwirizana ndi malo ovuta.
Njira imodzi yotereyi imatchedwa iontophoresis, kapena ionto, mwachidule. Njirayi imaphatikizapo chigamba chomwe chimayikidwa pa khungu lanu. Kuphatikizidwa pa chigamba ndi mankhwala ang'onoang'ono a mankhwala. Zonsezi ndi thumba zimagwirizanitsidwa ndi makina a ionto. Pamene mankhwala akuperekedwa kudzera m'magazi a khungu lanu, makina a ionto amagwiritsanso ntchito kanyumba kakang'ono kamagetsi. Mpweya wotsika womwe ukupitirirabe umapangitsa kuti khungu lanu likhale lopanda mankhwala.
Mankhwala a Ionto Dexamethasone ndi Zambiri
Ndi iontophoresis, n'zotheka kupanga pulogalamu ya mankhwala (m'malo momasula zonse mwakamodzi ndi / kapena pa mphamvu zonse).
Ionto ikhoza kupereka mankhwala osiyanasiyana monga a lidocane, peptides, ndi dexamethasone, malinga ndi kafukufuku wa 2006 wofalitsidwa mu magazini yotchedwa Expert Opinion on Drug Safety,
Lidocane ndiwopweteka kwambiri komanso wothandizira khungu lomwe limagwiritsanso ntchito mankhwala ena kunja kwa kuchuluka kwa mankhwala a mafupa.
Dexamethasone ndi corticosteroid yomwe imafanana ndi mahomoni ofunikira omwe amapangidwa mwachibadwa ndi adrenal glands. Dexamethasone ili ndi zotsutsana ndi zotupa, zomwe zikutanthauza kuti zimachepetsa kapena zimachepetsa kutupa, kutentha, kufiira ndi kupweteka. Amagwiritsidwanso ntchito monga chithandizo cha nyamakazi, bursitis ndi tendonitis, komanso matenda ena, kuphatikizapo khansa.
Mbiri ya Iontophoresis
Monga tafotokozera pamwambapa, ndi mankhwala a iontophoresis, mphamvu zamagetsi zimapereka mankhwala opatsirana kupweteka pamene imadutsa pamtambo wachitsulo (komanso ululu wa tsitsi).
M'mbuyomu, akatswiri amakhulupirira kuti iontophoresis imakhudza mankhwalawo pakhungu. Koma posachedwa, asintha malingaliro awo a momwe njirayi imagwirira ntchito. Kwenikweni, iwo amati ionto amathandiza kutulutsa pores tating'ono ting'onoting'ono ting'onoting'ono ting'onoting'ono ting'onoting'ono ting'onoting'ono ting'onoting'ono ting'onoting'ono ting'onoting'ono ting'onoting'ono ting'onoting'ono ting'onoting'ono ting'onoting'ono ting'onoting'ono ting'onoting'ono ting'onoting'ono ting'onoting'ono ting'onoting'ono ting'onoting'ono ting'onoting'ono ting'onoting'ono tomwe timatulutsa khungu.
M'tsogolo ndi Ionto
Iontophoresis ikukonzekera mwakhama ndi akatswiri ofufuza zamoyo zosiyanasiyana. Akatswiri akuyesera kuwonjezera luso la mankhwala kuti adziwe khungu lonse, komanso kuchepetsa zotsatira zake. Ndipo iwo ali ndi chidwi ndi mapulogalamu abwino operekera mankhwala. Kugwiritsa ntchito matebulo osiyanasiyana: Nanotechnology (kugwira ntchito ndi zinthu zing'onozing'ono ndi mitsinje,) miniaturization, electroporation (kuyambitsa DNA pogwiritsa ntchito magetsi kuti atsegule pores,) sonophoresis (chifukwa chowonjezera kumwa mankhwala) ndi kugwiritsa ntchito mankhwala zopititsa patsogolo.
Cholinga pa kufufuza kumeneku, ndithudi, ndi makina ovuta kwambiri a ionto. Monga chitsanzo cha kupititsa patsogolo, olemba a Expert Opinion on Research Drug Safety akuti fentanyl E-TRANS iontophoretic dongosolo linasinthidwa ndi "zotsatira zolimbikitsa."
Zimene muyenera kuyembekezera Mukapeza Iontophoresis
Mukakhala ndi mankhwala a iontophoresis, wodwala wodwalayo angakhale atagona pa gome la mankhwala. Adzaika magetsi awiri pafupi ndi malo ovuta (komwe kutupa kulipo.) Mmodzi wa electrodes adzakhala ndi mankhwala opweteka - kaya dexamethasone, lidocane kapena china.
Ma electrode adzakhala ogwirizana ndi makina a iontophoresis. Wothandizira amagwiritsa ntchito maulamuliro pa ionto kuti awononge kuchuluka kwa panopa mpaka pamene zolepheretsa kugwiritsira ntchito mankhwala operekedwa ndi khungu lanu lonse ndi magetsi akugonjetsedwa. Mwanjira iyi, kubweretsa mankhwala kwa minofu yanu yowonjezera kumapangidwira.
Iontophoresis imadziwika kuti imathandiza mankhwala apamwamba kuti agwire bwino kwambiri - mpaka kufika pamatumbo, ndi zotsatira zochepa, kapena zina . Koma zimathandizanso kugawa dexamethasone, lidocane, ndi zina ku malo akuluakulu.
Chithandizo cha ionto chimatha pakati pa 10 ndi 15 mphindi, ndipo chingaperekedwe musanayambe kapena mutaphunzira gawo lanu. Iko sikumvetsa chisoni, bwanji osagwiritsira ntchito nthawiyi ngati mutayambiranso kusangalala musanapite kunyumba - kapena asanamuike kuti agwire ntchito!
> Chitsime:
> Batheja P. Transdermal iontophoresis. Akatswiri Opanga Mankhwala Osokoneza Bongo. Jan 2006. https://www.ncbi.nlm.nih.gov/pubmed/16370945
> Dexamethasone Mtheradi. Webusaiti ya Medline Plus. April 2017 https://medlineplus.gov/druginfo/meds/a682792.html