Mtundu wa Mafuta Wopezeka mwa Anthu Amene Ali ndi IBD Angakhale Wokhudzana ndi Kutupa
Creeping mafuta ndi chinthu chopezeka kwa odwala omwe ali ndi Crohn's disease ndi ulcerative colitis (mitundu iwiri ya matenda opweteka kwambiri, kapena IBD ) yomwe sichimamvetsetsanso ndichipatala. Ndipotu, izi sizinaphunzire mozama, ngakhale kukhalapo kwa odwala omwe ali ndi matenda a Crohn kwadziwika kwa zaka makumi angapo. Matenda a Crohn amatchedwa Burrill Crohn, chifukwa ndi amene adayambitsa matendawa omwe kale ankatchedwa kuti legion.
Dr Crohn anafotokoza kusintha kwa minofu ya adipose (mankhwala othandizira, kapena mafuta) odwala omwe anali ndi matenda a Crohn.
Kodi Chakudya Chakudya N'chiyani?
Aliyense ali ndi mafuta m'thupi mwake, komanso mafuta ena m'mimba mwake. Pakati pa 15 ndi 30% mafuta a thupi amaonedwa ngati abwino, ngakhale athanzi. M'malo mongokhala mbali ya thupi lomwe silikuyenda, minofu ya adipose tsopano imadziwika ngati thupi lenileni. Icho chimakhala ndi ntchito ndipo imabisa mankhwala osiyanasiyana. Mtundu umodzi ndi mankhwala a cytokines, omwe agwirizanitsidwa ndi IBD chifukwa amapezeka ambiri mwa anthu omwe ali ndi matendawa kusiyana ndi anthu abwinobwino. Pakhala pali milandu yomwe inapezeka kuti matumbo opitirira makumi asanu ndi limodzi (50%) amapezeka mkati mwa mafuta okwawa. N'zosadabwitsa kuti kukhala ndi mafuta ambiriwa kumakhala ndi vuto lalikulu la matenda a Crohn.
Poyamba, mafuta odyetserako ankaganiza kuti akudziŵika ndi matenda a Crohn-ndiko kuti, atapezeka, wodwalayo ankaganiza kuti ali ndi Crohn's.
Nkhumba zowonongeka zimatha kuwonedwa pamakina a tomography . Komabe, posachedwapa zinafotokozedwa kuti odwala omwe ali ndi zilonda zam'mimba akhoza kukhala ndi mabala odyera. Chidziwitso chochulukirapo cha mafutawa mpaka pano chikugwiritsidwa ntchito pa matenda a Crohn, kotero pang'ono pokha amadziwika bwino pa ulcerative colitis kapena indeterminate colitis.
Kodi "Mafuta" Ndi Chiyani Mafuta Odyera?
Nkhumba zonenepa si zofanana ndi mtundu wa mafuta omwe tikhoza kuyanjana ndi kunenepa kwambiri kapena kunenepa kwambiri. Kukhala ndi mafutawa sikutanthauza kuti munthu ndi woposa thanzi, komanso sichikuthandizira kukhala wonenepa kwambiri kapena wochuluka kwambiri. Odwala ambiri omwe ali ndi matenda a Crohn amakhala pa chiwerengero chochepa cha thupi, kapena chiwerengero chabwino cha thupi. Sizimveka kuti wodwalayo ali ndi IBD kukhala woposa kunenepa kapena wochuluka, koma si zachilendo. Komabe, ambiri mwa theka la odwala onse omwe ali ndi matenda a Crohn awonetsedwa kuti ali ndi zokwawa pamatumbo.
Kodi Tingachite Chiyani Zokwawa Zokwawa?
Funso limodzi anthu omwe ali ndi IBD angafunse momwe angapewere nyama zokwawa kapena zomwe zingachitidwe ngati zilipo. Ngakhale takhala tikudziwa za izo kuyambira m'ma 1930, pali zovuta za kafukufuku pa zokwawa zokwawa. Sindimvetsetsa bwino lomwe momwe zimakhudzira maphunziro a IBD, ngakhale pali ziphunzitso zambiri. Zolingaliro zina zimayang'ana makamaka pa mankhwala omwe amadziwika ndi mafuta ndi momwe amakhudzira kutupa ndi njira yotupa. Kafukufuku wina adawonetsa kuti mafuta amathandizira kutukusira ndipo zomwe zikuwongolera mafuta okwawa zingakhale zoganizira za m'tsogolo.
Sizidziwikiranso chifukwa chake zimachitika. Kodi izi zimachitika pamaso pa IBD, ndipo ali ndi gawo pa chifukwa chake, kapena kodi ndi zotsatira za IBD? Izi ndi mafunso omwe kufufuza kuyenera kuyankhidwa, monga asayansi akuyamba kufotokoza mbali iyi ya IBD yomwe panopa yanyalanyazidwa.
Zotsatira:
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Sideri A, Bakirtzi K, Shih DQ, et al. "Chinthu P chimayambitsa mapuloteni otchedwa cytokine omwe amatulutsa mawonekedwe a mesenteric adipocytes omwe ali ndi matenda opatsirana." Ma Cellular and Molecular Gastroenterology ndi Hepatology. 2015: 1: 420-432. 6 Aug 2015.